[HTML][HTML] Apolipoprotein AI prevents regulatory to follicular helper T cell switching during atherosclerosis
DE Gaddis, LE Padgett, R Wu, C McSkimming… - Nature …, 2018 - nature.com
Regulatory T (Treg) cells contribute to the anti-inflammatory response during atherogenesis.
Here we show that during atherogenesis Treg cells lose Foxp3 expression and their …
Here we show that during atherogenesis Treg cells lose Foxp3 expression and their …
[HTML][HTML] Hypercholesterolemia enhances T cell receptor signaling and increases the regulatory T cell population
Hypercholesterolemia promotes the inflammation against lipoproteins in atherosclerosis.
Development of atherosclerosis is affected by the balance between pro-inflammatory …
Development of atherosclerosis is affected by the balance between pro-inflammatory …
Vaccination against Foxp3+ regulatory T cells aggravates atherosclerosis
T van Es, GHM van Puijvelde, AC Foks, KLL Habets… - Atherosclerosis, 2010 - Elsevier
OBJECTIVE: Regulatory T cells are crucial for immune homeostasis and an impaired
regulatory T cell function results in many pathological conditions. Regulatory T cells have …
regulatory T cell function results in many pathological conditions. Regulatory T cells have …
Differential effects of regulatory T cells on the initiation and regression of atherosclerosis
OBJECTIVE: Regulatory T cells (Tregs) play an important role in the regulation of T cell-
mediated immune responses through suppression of T cell proliferation and cytokine …
mediated immune responses through suppression of T cell proliferation and cytokine …
[HTML][HTML] Depletion of FOXP3+ regulatory T cells promotes hypercholesterolemia and atherosclerosis
R Klingenberg, N Gerdes, RM Badeau… - The Journal of …, 2013 - Am Soc Clin Investig
Atherosclerosis is a chronic inflammatory disease promoted by hyperlipidemia. Several
studies support FOXP3-positive regulatory T cells (Tregs) as inhibitors of atherosclerosis; …
studies support FOXP3-positive regulatory T cells (Tregs) as inhibitors of atherosclerosis; …
Pathogenic Autoimmunity in Atherosclerosis Evolves From Initially Protective Apolipoprotein B100–Reactive CD4+ T-Regulatory Cells
Background: Throughout the inflammatory response that accompanies atherosclerosis,
autoreactive CD4+ T-helper cells accumulate in the atherosclerotic plaque. Apolipoprotein …
autoreactive CD4+ T-helper cells accumulate in the atherosclerotic plaque. Apolipoprotein …
Atherosclerosis-Driven Treg Plasticity Results in Formation of a Dysfunctional Subset of Plastic IFNγ+ Th1/Tregs
MJ Butcher, AR Filipowicz, TC Waseem… - Circulation …, 2016 - Am Heart Assoc
Rationale: Forkhead box P3+ T regulatory cells (Tregs) are key players in maintaining
immune homeostasis. Evidence suggests that Tregs respond to environmental cues to …
immune homeostasis. Evidence suggests that Tregs respond to environmental cues to …
Role of Naturally Occurring CD4+CD25+ Regulatory T Cells in Experimental Atherosclerosis
A Mor, D Planer, G Luboshits, A Afek… - … , and vascular biology, 2007 - Am Heart Assoc
Objective—Naturally occurring CD4+ CD25+ regulatory T cells (Tregs) exert suppressive
effects on effector CD4 cells and downregulate experimental autoimmune disorders. We …
effects on effector CD4 cells and downregulate experimental autoimmune disorders. We …
Regulatory T cells in atherosclerosis: critical immune regulatory function and therapeutic potential
Atherosclerosis is a chronic inflammatory disease that is mediated by innate and adaptive
immune responses. The disease is characterized by sub-endothelial accumulation and …
immune responses. The disease is characterized by sub-endothelial accumulation and …
[HTML][HTML] Statins induce the accumulation of regulatory T cells in atherosclerotic plaque
X Meng, K Zhang, J Li, M Dong, J Yang, G An, W Qin… - Molecular …, 2012 - Springer
Abstract CD4+ CD25+ regulatory T cells (Tregs) mediate immune suppression and prevent
autoimmune disorders. Recently, Tregs were found to present in atherosclerotic lesions and …
autoimmune disorders. Recently, Tregs were found to present in atherosclerotic lesions and …