Neutrophils, the most copious leukocytes in human blood, play a critical role in
tumorigenesis, cancer progression, and immune suppression. Recently, neutrophils have …

Over the last decades, cancer immunotherapies such as checkpoint blockade and adoptive
T cell transfer have been a game changer in many aspects and have improved the treatment …

There is growing recognition that neutrophils play an important role in cancer initiation,
progression and metastasis. Although they are typically characterized as short-lived effector …

The immune checkpoint blockade-based immunotherapies are revolutionizing cancer
management. Tumor-associated neutrophils (TANs) were recently highlighted to have a …

Neutrophils play a Janus-faced role in the complex landscape of cancer pathogenesis and
immunotherapy. As immune defense cells, neutrophils release toxic substances, including …

Simple Summary Neutrophils are the most abundant leukocytes in the circulation, represent
the first line of defense in the immune system and mediate inflammation. Increasing …

Neutrophils, the most abundant circulating leukocytes in human, play an indispensable role
in the innate immune response to microbial infections. However, the contribution of tumor …

The crosstalk between cancer cells and the immune system is crucial for disease
progression and its therapeutic targeting is providing exciting results, in particular with newly …

The interaction between cancer cells and immune cells is important for the cancer
development. However, much attention has been given to T cells and macrophages. Being …

Over the past decade, research has prominently established neutrophils as key contributors
to the intricate landscape of tumor immune biology. As polymorphonuclear granulocytes …