Hormones and neurotransmitters are released through fluctuating exocytotic fusion pores
that can flicker open and shut multiple times. Cargo release and vesicle recycling depend on …

Flickering of fusion pores during exocytotic release of hormones and neurotransmitters is
well documented, but without assays that use biochemically defined components and …

The initial, nanometer-sized connection between the plasma membrane and a hormone-or
neurotransmitter-filled vesicle–the fusion pore–can flicker open and closed repeatedly …

Neurotransmitter and hormone release involve calcium‐triggered fusion of a cargo‐loaded
vesicle with the plasma membrane. The initial connection between the fusing membranes …

Ca2+-triggered exocytosis functions broadly in the secretion of chemical signals, enabling
neurons to release neurotransmitters and endocrine cells to release hormones. The …

Calcium-triggered exocytotic release of neurotransmitters and hormones from neurons and
neuroendocrine cells underlies neuronal communication, motor activity and endocrine …

During exocytosis, fusion pores form the first aqueous connection that allows escape of
neurotransmitters and hormones from secretory vesicles. Although it is well established that …

Exocytosis is a multistage process involving a merger between the vesicle and the plasma
membranes, leading to the formation of a fusion pore, a channel, through which secretions …

Here we introduce ApoE-based nanolipoprotein particle (NLP) a soluble, discoidal bilayer
mimetic of∼ 23 nm in diameter, as fusion partners to study the dynamics of fusion pores …

Intercellular communication is commonly mediated by the regulated fusion, or exocytosis, of
vesicles with the cell surface. SNARE (soluble N-ethymaleimide sensitive factor attachment …