Insufficient tumor penetration is one of the major obstacles for satisfactory cancer therapy. As
a result, the ability to push the lower limits of size for nanoparticle platforms that have …

Strategies for the development of anticancer drug delivery systems have undergone a
dramatic transformation in the last few decades. Lipid-based drug delivery systems, such as …

Despite the wide use of paclitaxel (PTX) as antitumor drug, its intravenous administration is
still limited by the low aqueous solubility (< 1.0 μg/mL; log P= 3.96). Taxol® is the main …

Lack of cancer-targeted delivery of chemotherapeutics is one of the major obstacles for
successful cancer therapy. Nanostructured lipid carriers (NLC) have shown great promise in …

In the present study, we constructed a tumor-targeting and pH-sensitive lipoprotein-mimic
nanocarrier containing paclitaxel (FA-BSA-LC/DOPE-PTX), by adding 1, 2-dioleoyl-sn …

Irinotecan loaded nanostructured lipid carrier (NLC-Ir) was surface decorated with
hyaluronic acid graft polymer. Hyaluronic acid is a biocompatible, non-antigenic and …

The hydrophilic drug Doxorubicin hydrochloride (DOX) paired with oleic acid (OA) was
successfully incorporated into nanostructured lipid carriers (NLCs) by a high-pressure …

The aim of our study was to develop hyaluronic acid-coated, paclitaxel-loaded,
nanostructured lipid carriers (HA-NLCs) prepared via electrostatic attraction for delivering …

In the present study, cholesterol nanostructured lipid carriers with various oleic acid content
loaded with paclitaxel (PTX) were prepared by solvent emulsification‐diffusion method using …

Stearyl-2-amino-2-deoxyglucose (2-DG) modified nanostructured lipid carriers (NLC) were
developed as novel vehicles for tumor-targeted delivery. The NLC were prepared using a …