Liver fibrosis is an excessive accumulation of extracellular matrix (ECM) due to chronic liver
injury. In recent years, the mechanism of liver fibrosis has been extensively studied. Hepatic …

Liver fibrosis is a typical complication of chronic liver diseases resulting in cirrhosis that
remains a major public health problem. The aim of the present study was to identify the role …

Aims This study aimed to elucidate the role of Interleukin-11 (IL-11) in hepatic fibrosis (HF)
and its potential as a therapeutic target for HF treatment. Materials and methods We …

Interleukin‐18 signaling promotes activation of hepatic stel... : Hepatology Interleukin‐18
signaling promotes activation of hepatic stellate cells in mouse liver fibrosis : Hepatology AASLD …

Background Inflammatory cytokines play key pathogenic roles in liver fibrosis. IL-15 is a
proinflammatory cytokine produced by myeloid cells. IL-15 promotes pathogenesis of …

Backgrounds & Aims: Immunomodulatory cytokines, including interleukin-10 (IL-10), may
mediate hepatic fibrosis. Methods: We generated transgenic (TG) mice with hepatocyte …

Background: Interleukin-1 (IL-1) β and IL-1 receptor antagonist (IL-1Ra) have been
proposed as important mediators during chronic liver diseases. We aimed to determine …

Hepatic fibrosis is a wound healing process which results in deposition of excessive
abnormal extracellular matrix (ECM) in response to various liver injuries. Activated hepatic …

IL-19 is a cytokine discovered by homologous searching with IL-10 and is produced by non-
immune cells, such as keratinocytes, in addition to immune cells, such as macrophages …

Background Interleukin-8 (IL-8, CXCL8) is a potent chemoattractant for neutrophils and
contributes to acute liver inflammation. Much less is known about IL-8 in chronic liver …