Disrupted protein folding or decreased protein stability can lead to the accumulation of
(partially) un‐or misfolded proteins, which ultimately cause the formation of protein …

The aggregation of specific proteins is hypothesized to cause several pathological
conditions, which are collectively known as amyloid disorders. The aggregation of peptides …

Understanding the mechanisms underlying protein misfolding and aggregation has become
a central issue in biology and medicine. Compelling evidence show that the formation of …

Protein and peptide aggregation raises keen interest due to their involvement in number of
pathological conditions ranging from neurodegenerative disorders to systemic amyloidosis …

Protein aggregation is an important phenomenon that alternatively is part of the normal
functioning of nature or, central to this review, has negative consequences via its …

Amyloidogenic diseases are characterised by the formation of amyloid aggregates inside or
outside the cell. Amyloid-associated human diseases include Alzheimer's disease …

Protein and peptides are converted from their soluble forms into highly ordered fibrillar
aggregates under various conditions inside the cell. Such transitions confer diverse …

Uncontrolled protein aggregation is a constant challenge in all compartments of living
organisms. The failure of a peptide or protein to remain soluble often results in pathology. So …

Protein aggregation is a widespread phenomenon that stems from the establishment of non-
native intermolecular contacts resulting in protein precipitation. Despite its deleterious …

Protein function and flexibility is directly related to the native distribution of its structural
elements and any alteration in protein architecture leads to several abnormalities and …