Pain is a common symptom that can be complex to treat. Analgesic medications are the
mainstay treatment, but there is wide interindividual variability in analgesic response and …

Pharmacogenomics is the study of genetic variants that impact drug effects through changes
in a drug's pharmacokinetics and pharmacodynamics. Pharmacogenomics is being …

The experience of chronic pain is one of the commonest reasons for seeking medical
attention, being a major issue in clinical practice. While pain is a universal experience, only …

This paper reviews the impact of genetic variability of drug metabolizing enzymes,
transporters, receptors, and pathways involved in chronic pain perception on the efficacy …

Objective: To provide an overview of clinical recommendations regarding genomic medicine
relating to pain management and opioid use disorder. Data Sources: A literature review was …

Genetic research heralds a new therapeutic approach to pain management. Increasing
literature demonstrates individual genetic vulnerabilities to specific pain types and …

Abstract Purpose of Review Pain is multifactorial and complex, often with a genetic
component. Pharmacogenomics is a relative new field, which allows for the development of …

Physicians continue to struggle with the clinical management of pain, in part because of the
large interindividual variability in the efficacy, occurrence of side effects and undesired …

Objective The experience of chronic pain is one of the commonest reasons individuals seek
medical attention, making the management of chronic pain a major issue in clinical practice …

Medicine has been continuously challenged, as well as stimulated, by the extraordinary
variability in patient response to pharmacotherapy. The new age of identification of risk …