Immunoregulation of human natural killer cells (NK) by corticosteroids: inhibitory effect of culture supernatants

MPN Nair, SA Schwartz - Journal of allergy and clinical immunology, 1988 - Elsevier
Peripheral blood lymphocytes were separated into HNK-l+ and HNK-l− subpopulations and
examined for the effects of prednisolone (PRD) on natural killer cell activities in vitro …

Immunomodulatory effects of corticosteroids on natural killer and antibody-dependent cellular cytotoxic activities of human lymphocytes.

MP Nair, SA Schwartz - Journal of immunology (Baltimore, Md …, 1984 - journals.aai.org
The in vitro effect of prednisolone (PRD) on NK and ADCC activities of human lymphocytes
was investigated. PRD at concentrations ranging from 7.5 X 10 (-3) to 1 X 10 (-5) M …

[引用][C] Characterization and functions of natural killer cells

JR Ortaldo, BJ Mathieson, RH Wiltrout - Annales de l'Institut Pasteur …, 1988 - Elsevier
Natural killer (NK) cells have spontaneous cytotoxic activity which can be augmented or
suppressed by a wide range of stimuli [1, 2], and which does not depend on prior …

Suppression of the natural killer cell activity of murine spleen cell cultures by dexamethasone

WI Cox, NJ Holbrook, RJ Grasso… - Proceedings of the …, 1982 - journals.sagepub.com
Investigations into the mode of action of glucocorticoids on natural killer (NK) cell activity
have been hindered by the lack of an in vitro model system. We report that the NK activity of …

Effect of cortisol on the native and in vitro induced non-MHC restricted cytotoxicity of large granular lymphocytes.

L Matera, E Cardoso, F Veglia, A Cesano… - Journal of clinical & …, 1988 - europepmc.org
Natural Killer (NK) activity has been shown to be depressed under stressful conditions.
Glucocorticoids, which are known to increase during stress, seem to negatively regulate the …

Characterization of the in Vitro Effects of Glucocorticosteroids on NK Cell Activity

BK Pedersen, JM Beyer - Allergy, 1986 - Wiley Online Library
The NK cell activity of mononuclear cells as well as monocyte‐depleted, Percoll‐
fractionated, NK cell‐enriched effector cells against K 562 target cells was inhibited by …

Characterization of corticosteroid receptors in natural killer cells: comparison with circulating lymphoid and myeloid cells

P Katz, AM Zaytoun, JH Lee Jr - Cellular immunology, 1985 - Elsevier
Lymphocytes mediating natural killer (NK.) and antibody-dependent cellular cytotoxicity
(ADCC) activities are relatively refractory to the changes in circulatory traffic and intrinsic …

Differential effects of histamine receptor antagonists on human natural killer cell activity

K Hellstrand, S Hermodsson - International Archives of Allergy and …, 1987 - karger.com
In this study we investigated the modulation of natural killer (NK) cell activity by various
histamine receptor antagonists in vitro. The histamine H2-receptor antagonists cimetidine …

Natural killer cell activity in the rat. Analysis of effector cell morphology and effects of interferon on natural killer cell function in the athymic (nude) rat

CW Reynolds, TT Timonen, HT Holden… - European journal of …, 1982 - Wiley Online Library
Athymic (nude) rats were found to have increased levels of natural killer (NK) activity, 3− to
5− fold higher than in euthymic rats. Studies were performed to determine the nature of the …

Characterization of the in vivo and in vitro effects of indomethacin on human natural killer cell activity

BK Pedersen, P Oxholm, K Klarlund - Allergy, 1986 - Wiley Online Library
The in vivo and in vitro effects of indomethacin on the natural killer (NK) cell activity against
K 562 target cells were studied In vivo administration of indomethacin, 3× 50 mg for 7 days …