Aquaporins are tetrameric membrane-bound channels that facilitate transport of water and
other small solutes across cell membranes. In eukaryotes, they are frequently regulated by …

Since the discovery of Aquaporin-1 (AQP1) as a water channel, many studies have revealed
the importance of aquaporins in mammalian physiology and pathophysiology as well as …

Aquaporins (AQPs) are expressed in physiologically essential tissues and organs in which
edema and fluid imbalances are of major concern. Potential roles in brain water …

Background Insight into protein–protein interactions (PPIs) is highly desirable in order to
understand the physiology of cellular events. This understanding is one of the challenges in …

Over the past decade, significant advances have been made in understanding how water
moves in to and out of cells. Investigators have used molecular and structural biological …

The aquaporin field has matured at an exceptionally fast pace and we are at the verge to
develop serious strategies to therapeutically modulate aquaporin function directly or via …

The discovery of the water channel aquaporin has greatly expanded our understanding of
the regulation of the water permeability of biological membranes. The atomic structure of …

The aquaporin protein family performs fundamental tasks in the physiology of several
organs in the human body. Their roles in several disorders known to involve water …

Water is the major component of cells and tissues throughout all forms of life. Fluxes of water
and solutes through cell membranes and epithelia are essential for osmoregulation and …

Aquaporin-mediated water transport across cellular membranes is an ancient, ubiquitous
mechanism within cell biology. This family of integral membrane proteins includes both …