Overcoming the vaginal barrier to achieve sufficient drug penetration and retention is a huge
obstacle for drug delivery in chemotherapeutics for cervical cancer. In this study, we …

Electrospun composite nanofibrous scaffolds have been regarded as a potential carrier for
local drug delivery to prevent tumor recurrence. Herein, a model drug (paclitaxel) was …

Polymer-based local drug delivery system may be suitable for the treatment of cervix cancer.
A pilot study was carried out to examine the efficacy of cisplatin-loaded poly (ethylene …

A small scale study was carried out to investigate the therapeutic efficacy cisplatin loaded
poly-caprolactone/chitosan composite electrospun nanofibers for local chemotherapy of …

Local delivery of chemotherapeutics in the cervicovaginal tract using nanoparticles may
reduce adverse side effects associated with systemic chemotherapy, while improving …

Purpose Co-delivery of two or more drugs into the same cancer cells or tissues in the same
nanocarriers provides a new paradigm in cancer treatment. In this study, two kinds of …

The aim of the present study is to design a mucoadhesive nano-carrier system which retains
at the site of application and maximizes the therapeutic potential of anticancer drug as well …

Abstract pH-sensitive polyvinyl alcohol/polycaprolactone (PVA/PCL) core-shell nanofibers
were successfully fabricated by coaxial electrospinning method, in which PVA and PCL …

Because of the complexity of cancer, a combination of chemotherapy and gene therapy is an
emerging treatment modality. To realize the full potential of this strategy, a smart, highly …

Recently, implantable electrospun nanofiber-based drug delivery devices have acquired a
great interest in treating a tissue defect after tumor resection. In current work, Curcumin …