[HTML][HTML] Role of neuron and glia in Alzheimer's disease and associated vascular dysfunction
S Bandyopadhyay - Frontiers in aging neuroscience, 2021 - frontiersin.org
Amyloidogenicity and vascular dysfunction are the key players in the pathogenesis of
Alzheimer's disease (AD), involving dysregulated cellular interactions. An intricate balance …
Alzheimer's disease (AD), involving dysregulated cellular interactions. An intricate balance …
Pathophysiological role of microglial activation induced by blood-borne proteins in Alzheimer's disease
S Kim, C Sharma, UJ Jung, SR Kim - Biomedicines, 2023 - mdpi.com
The blood–brain barrier (BBB) restricts entry of neurotoxic plasma components, blood cells,
and pathogens into the brain, leading to proper neuronal functioning. BBB impairment leads …
and pathogens into the brain, leading to proper neuronal functioning. BBB impairment leads …
Dissecting the contribution of vascular alterations and aging to Alzheimer's disease
C Janota, CA Lemere, MA Brito - Molecular neurobiology, 2016 - Springer
Alzheimer's disease (AD) is a neurodegenerative disease characterized by cognitive decline
that afflicts as many as 45% of individuals who survive past the age of 85. AD has been …
that afflicts as many as 45% of individuals who survive past the age of 85. AD has been …
[HTML][HTML] Peripheral pathways to neurovascular unit dysfunction, cognitive impairment, and Alzheimer's Disease
AR Nelson - Frontiers in Aging Neuroscience, 2022 - frontiersin.org
Alzheimer's disease (AD) is the most common form of dementia. It was first described more
than a century ago, and scientists are acquiring new data and learning novel information …
than a century ago, and scientists are acquiring new data and learning novel information …
The neurovascular unit dysfunction in Alzheimer's disease
LO Soto-Rojas, M Pacheco-Herrero… - International Journal of …, 2021 - mdpi.com
Alzheimer's disease (AD) is the most common neurodegenerative disease worldwide.
Histopathologically, AD presents with two hallmarks: neurofibrillary tangles (NFTs), and …
Histopathologically, AD presents with two hallmarks: neurofibrillary tangles (NFTs), and …
Interactions between glial cells and the blood-brain barrier and their role in Alzheimer's disease
M Zhao, XF Jiang, HQ Zhang, JH Sun, H Pei… - Ageing research …, 2021 - Elsevier
Abstract Alzheimer's disease (AD), which is an irreversible neurodegenerative disorder
characterized by senile plaques and neurofibrillary tangles, is the most common form of …
characterized by senile plaques and neurofibrillary tangles, is the most common form of …
Vascular risk factors and Alzheimer's disease: blood-brain barrier disruption, metabolic syndromes, and molecular links
JT He, X Zhao, L Xu, CY Mao - Journal of Alzheimer's Disease, 2020 - content.iospress.com
Alzheimer's disease (AD) is a neurodegenerative disorder, marked by cortical and
hippocampal deposition of amyloid-β (Aβ) plaques and neurofibrillary tangles and cognitive …
hippocampal deposition of amyloid-β (Aβ) plaques and neurofibrillary tangles and cognitive …
[HTML][HTML] Neurovascular dysfunction and neurodegeneration in dementia and Alzheimer's disease
AR Nelson, MD Sweeney, AP Sagare… - Biochimica et Biophysica …, 2016 - Elsevier
Vascular insults can initiate a cascade of molecular events leading to neurodegeneration,
cognitive impairment, and dementia. Here, we review the cellular and molecular …
cognitive impairment, and dementia. Here, we review the cellular and molecular …
Emerging roles of astrocytes in blood-brain barrier disruption upon amyloid-beta insults in Alzheimer's disease
Blood-brain barrier disruption occurs in the early stages of Alzheimer's disease. Recent
studies indicate a link between blood-brain barrier dysfunction and cognitive decline and …
studies indicate a link between blood-brain barrier dysfunction and cognitive decline and …
The potential role of cytokines and growth factors in the pathogenesis of Alzheimer's disease
G Ogunmokun, S Dewanjee, P Chakraborty… - Cells, 2021 - mdpi.com
Alzheimer's disease (AD) is one of the most prominent neurodegenerative diseases, which
impairs cognitive function in afflicted individuals. AD results in gradual decay of neuronal …
impairs cognitive function in afflicted individuals. AD results in gradual decay of neuronal …