Emerging drugs for malaria

S Tschan, PG Kremsner… - Expert opinion on …, 2012 - Taylor & Francis
Introduction: Malaria remains one of the most important infectious diseases, causing around
655 000 deaths annually, mostly among children in Sub-Saharan Africa. Plasmodium …

New medicines to combat malaria: an overview of the global pipeline of therapeutics

TNC Wells - Treatment and Prevention of Malaria: Antimalarial Drug …, 2012 - Springer
Over the last 5 years, there has been an increased investment in malaria medicines, with the
emergence of a range of new fixed dose artemisinin combination therapies (FACTs). Of the …

Antimalarial drugs: current status and new developments

D Rathore, TF McCutchan, M Sullivan… - Expert opinion on …, 2005 - Taylor & Francis
Malaria continues to be a major threat in the developing world, with> 1 million clinical
episodes and 3000 deaths every day. In the last century, malaria claimed between 150 and …

Pharmacotherapy for artemisinin-resistant malaria

E Koehne, AA Adegnika, J Held… - Expert Opinion on …, 2021 - Taylor & Francis
Introduction Malaria, the most devastating parasitic disease, is currently treated with
artemisinin-based combination therapies (ACTs). Unfortunately, some ACTs are unable to …

Malaria: an update on current chemotherapy

BJ Visser, M van Vugt, MP Grobusch - Expert opinion on …, 2014 - Taylor & Francis
Introduction: Chemotherapy of malaria has become a rapidly changing field. Less than two
decades ago, treatment regimens were increasingly bound to fail due to emerging drug …

Malaria chemotherapy: recent advances in drug development

S Gemma, V Travagli, L Savini… - Recent patents on …, 2010 - ingentaconnect.com
Malaria is a disease caused by parasitic protozoa of the genus Plasmodium. Despite
significant advances in understanding the disease and the parasite biology, malaria still …

Antimalarial drug discovery: recent progress and future directions

F Calderón, DM Wilson, FJ Gamo - Progress in medicinal chemistry, 2013 - Elsevier
Malaria is still today one of the deadliest infectious diseases affecting a huge proportion of
the world population, hitting with special virulence those people living in the least developed …

Advances in antimalarial drug evaluation and new targets for antimalarials

G Philippe, D Christiane, F Isabelle - Malaria Parasites, 2012 - books.google.com
Parasitic infections due to the protozoa Plasmodium are responsible for malaria, a severe
disease that still caused about 225 million cases and 781,000 human deaths in 2009 …

[HTML][HTML] When is enough enough? The need for a robust pipeline of high-quality antimalarials

TN Wells, EM Poll - Discovery medicine, 2010 - discoverymedicine.com
Malaria kills an estimated one million people a year--mostly children under 5. State-of-the-
art medicines known as artemisinin combination therapies (ACTs) are available, and …

Novartis Malaria Initiative: best practice example of pharmaceutical industry's engagement in the fight against malaria

G Lefevre, AC Marrast… - Annals of the New York …, 2011 - Wiley Online Library
Despite considerable advances in the treatment and prevention of malaria, Plasmodium
falciparum is still a threat to millions of people across the world, particularly in sub‐Saharan …