Although powerful adjuvants hold promise of vaccines for cancer immunotherapy,
cumbersome preparation processes, elusive mechanisms and failure to induce T cell …

Adjuvants play an important role in enhancing vaccine‐induced immune protection.
Adequate cellular uptake, robust lysosomal escape, and subsequent antigen cross …

Nanoparticles have been regarded as a promising vaccine adjuvant due to their innate
immune potentiation and enhanced antigen transport. However, the inefficient infiltration into …

Amino acid-tuned self-assembly has become an attractive strategy for constructing various
functional materials. Here, a series of dibenzocyclooctyne (DIBO) functionalized amphiphilic …

Peptide vaccine targeting tumor-specific antigens is a promising cancer treatment regimen.
However, peptide vaccines are commonly low-immunogenic, leading to suboptimal …

Background: Neoantigen nanovaccine has been recognized as a promising treatment
modality for personalized cancer immunotherapy. However, most current nanovaccines are …

Immunostimulatory cues play an important role in priming antitumor immunity and promoting
the efficacy of subunit cancer vaccines. However, the clinical use of many …

We utilize the supramolecular self-assembling peptide of Nap-GDFDFDYDK to construct
chemically programmed, self-assembling and self-adjuvant MUC1-based antitumor …

Biomimetic nanoparticles have potential applications in many fields due to their favorable
properties. Here, we developed a self-adjuvanting biomimetic anti-tumor nanovaccine …

Insufficient activation of the anti-tumor immune response generally limits the efficacy of
immunotherapy in malignant tumors. However, efficiently activating anti-tumor cellular and …