Human cytochrome P450 1B1 (CYP1B1) is an extrahepatic heme-containing
monooxygenase. CYP1B1 contributes to the oxidative metabolism of xenobiotics, drugs, and …

Abstract Human cytochrome P450 1B1 (CYP1B1) is involved in the metabolism of various
drugs. This enzyme catalyzes the hydroxylation of aryl compounds, thus generating more …

Human cytochrome P450 enzymes (CYPs) play a critical role in various biological
processes and human diseases. CYP1 family members, including CYP1A1, CYP1A2, and …

CYP4B1 belongs to the mammalian CYP4 enzyme family that also includes CYP4A, 4F, 4V,
4X, and 4Z subfamilies. CYP4B1 shares with other CYP4 proteins a capacity to ω …

Cytochrome P450 4B1 (CYP4B1) plays crucial roles in biotransforming of xenobiotics. Its
predominant extrahepatic expression has been associated with certain tissue-specific …

Abstract Human cytochrome P450 (CYP) 1B1 is a major enzyme for carcinogenic estrogen
metabolism and involved in the metabolic activation of procarcinogens of the polycyclic …

Cytochrome P450 1B1 is one of the main extra-hepatic cytochromes and has been
investigated for its ability to metabolize both exogenous and endogenous compounds into …

CYP1B1, a recently described dioxin inducible oxidoreductase, is a member of the
cytochrome P450 superfamily involved in the metabolism of estradiol, retinol, benzo [a] …

Cytochrome P450 isozymes (CYPs) from the CYP1 and CYP2 families located primarily in
extra-hepatic tissues represent ideal candidates for chemotherapeutic drug development …

Cytochrome P450 CYP1B1 is a relatively recently identified member of the CYP1 gene
family. The purpose of this commentary is to review the regulatory mechanisms, metabolic …