Melatonin (MEL) is an endogenous neurohormone with many biological functions, including
a powerful antioxidant effect. The aim of the present study was to determine whether MEL …

Hyperbaric oxygen (HBO) is a widely used treatment modality in many diseases. A known
side‐effect of HBO is the production of reactive oxygen species (ROS). Many anti‐oxidants …

Background It is well documented that the nitric oxide (NO) might be directly involved in
brain response to hypobaric hypoxia, and could contribute to memory deficiencies. Recent …

Obstructive sleep apnea (OSA) patients suffer from intermittent hypoxia (IH) and
neuropsychologic impairments. Oxidative stress is involved in the pathogenesis of OSA, so …

Objective: In the present study, we investigated the putative protective effect of melatonin
and amlodipine against ischemia/reperfusion (I/R)-induced brain damage. Material and …

This study investigated the potential of melatonin in ameliorating hypoxic damage to the
periventricular white matter (PWM) in the neonatal brain. Vascular endothelial growth factor …

In addition to its beneficial effects, hyperbaric oxygen (HBO) exposure causes some
detrimental effects via oxidative stress. Previous experimental studies showed that …

ABSTRACT Melatonin (N-acetyl-5-methoxytryptamine) is the main secretory product of the
pineal gland in all mammals including humans, but it is also produced in other organs. It has …

In the present study, we tried to investigate the effects of melatonin, a novel antioxidant and
a potent free radical scavenger, in stress-induced cerebral, cerebellar, cardiac, and hepatic …

Hypoxia in preterm infants is a clinical condition that has been associated with cognitive and
behavioral disturbances for which treatment strategies are strongly required. Melatonin …