[HTML] nih.gov

[HTML][HTML] EGF induces epithelial-mesenchymal transition and cancer stem-like cell properties in human oral cancer cells via promoting Warburg effect

Q Xu, Q Zhang, Y Ishida, S Hajjar, X Tang, H Shi… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Abstract “Warburg effect”, the enhanced glycolysis or aerobic glycolysis, confers cancer cells
the ability to survive and proliferate even under stressed conditions. In this study, we …
被引用次数：109 相关文章 所有 10 个版本
[PDF] wiley.comFull View

EGFR enhances the stemness and progression of oral cancer through inhibiting autophagic degradation of SOX2

XX Lv, XY Zheng, JJ Yu, HR Ma, C Hua… - Cancer …, 2020 - Wiley Online Library
Epidermal growth factor receptor (EGFR) is highly expressed in head and neck squamous
cell carcinoma (HNSCC) and correlates with poor prognosis. EGFR has been demonstrated …
被引用次数：42 相关文章 所有 6 个版本
[HTML] nih.gov

[HTML][HTML] IGF2BP2 promotes cell invasion and epithelial-mesenchymal transition through Src-mediated upregulation of EREG in oral cancer

CW Lin, WE Yang, CW Su, HJ Lu, SC Su… - International Journal of …, 2024 - ncbi.nlm.nih.gov
Insulin-like growth factor 2 mRNA binding protein 2 (IGF2BP2), with high affinity to a myriad
of RNA transcripts, has been shown to elicit promotive effects on tumorigenesis and …
被引用次数：2 相关文章 所有 5 个版本
[HTML] plos.org

[HTML][HTML] EGFR kinase promotes acquisition of stem cell-like properties: a potential therapeutic target in head and neck squamous cell carcinoma stem cells

EL Abhold, A Kiang, E Rahimy, SZ Kuo… - PloS one, 2012 - journals.plos.org
Members of the EGFR/ErbB family of tyrosine kinases are found to be highly expressed and
deregulated in many cancers, including head and neck squamous cell carcinoma (HNSCC) …
被引用次数：111 相关文章 所有 15 个版本
[HTML] springer.comFull View

[HTML][HTML] A transcriptomic map of EGFR-induced epithelial-to-mesenchymal transition identifies prognostic and therapeutic targets for head and neck cancer

H Schinke, E Shi, Z Lin, T Quadt, G Kranz, J Zhou… - Molecular Cancer, 2022 - Springer
Background Epidermal growth factor receptor (EGFR) is both a driver oncogene and a
therapeutic target in advanced head and neck squamous cell carcinoma (HNSCC) …
被引用次数：30 相关文章 所有 13 个版本
[HTML] nih.gov

Glycometabolic reprogramming-mediated proangiogenic phenotype enhancement of cancer-associated fibroblasts in oral squamous cell carcinoma: role of PGC-1α …

X Li, E Jiang, H Zhao, Y Chen, Y Xu, C Feng… - British Journal of …, 2022 - nature.com
Background Angiogenesis is a key rate-limiting step in the process of tumour progression.
Cancer-associated fibroblasts (CAFs), the most abundant component OSCC stroma, play …
被引用次数：11 相关文章 所有 4 个版本
[HTML] nih.gov

Grainyhead-like 2 reverses the metabolic changes induced by the oncogenic epithelial–mesenchymal transition: effects on anoikis

JC Farris, PM Pifer, L Zheng, E Gottlieb, J Denvir… - Molecular Cancer …, 2016 - AACR
Resistance to anoikis is a prerequisite for tumor metastasis. The epithelial-to-mesenchymal
transition (EMT) allows tumor cells to evade anoikis. The wound-healing regulatory …
被引用次数：43 相关文章 所有 11 个版本
[HTML] sciencedirect.com

[HTML][HTML] Targeting the Warburg effect: A revisited perspective from molecular mechanisms to traditional and innovative therapeutic strategies in cancer

M Liao, D Yao, L Wu, C Luo, Z Wang, J Zhang… - … Pharmaceutica Sinica B, 2023 - Elsevier
Cancer reprogramming is an important facilitator of cancer development and survival, with
tumor cells exhibiting a preference for aerobic glycolysis beyond oxidative phosphorylation …
被引用次数：6 相关文章 所有 5 个版本
[HTML] nih.gov

[HTML][HTML] EGF-reduced Wnt5a transcription induces epithelial-mesenchymal transition via Arf6-ERK signaling in gastric cancer cells

Y Zhang, J Du, J Zheng, J Liu, R Xu, T Shen, Y Zhu… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Wnt5a, a ligand for activating the non-canonical Wnt signaling pathway, is commonly
associated with Epithelial-to-mesenchymal transition (EMT) in cancer cell metastasis. Here …
被引用次数：62 相关文章 所有 8 个版本
[PDF] researchgate.net

Cancer‐associated fibroblasts secrete hypoxia‐induced serglycin to promote head and neck squamous cell carcinoma tumor cell growth in vitro and in vivo by …

J Xie, X Qi, Y Wang, X Yin, W Xu, S Han, Y Cai, W Han - Cellular Oncology, 2021 - Springer
Background The tumor microenvironment (TME) is known to play a prominent role in the
pathology of head and neck squamous cell carcinoma (HNSCC). Cancer-associated …
被引用次数：23 相关文章 所有 5 个版本