Multi-omics approaches in colorectal cancer screening and diagnosis, recent updates and future perspectives

I Ullah, L Yang, FT Yin, Y Sun, XH Li, J Li, XJ Wang - Cancers, 2022 - mdpi.com
Simple Summary Colorectal cancer (CRC) is one of the most prevalent cancers worldwide.
Due to the absence of specific early symptoms, most of CRC patients are often diagnosed at …

Integrated analysis of multi-omics data for the discovery of biomarkers and therapeutic targets for colorectal cancer

N Zafari, P Bathaei, M Velayati… - Computers in Biology …, 2023 - Elsevier
The considerable burden of colorectal cancer and the rising trend in young adults
emphasize the necessity of understanding its underlying mechanisms, providing new …

[HTML][HTML] Diagnostic and therapeutic biomarkers in colorectal cancer: a review

JV de Assis, LA Coutinho, IT Oyeyemi… - American Journal of …, 2022 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is a public health concern and the second most common type of
cancer among men and women causing a significant mortality. Biomarkers closely linked to …

[HTML][HTML] New trends in molecular and cellular biomarker discovery for colorectal cancer

P Aghagolzadeh, R Radpour - World journal of gastroenterology, 2016 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is the third leading cause of cancer death worldwide, which is
consequence of multistep tumorigenesis of several genetic and epigenetic events. Since …

Proteomics, genomics and transcriptomics: their emerging roles in the discovery and validation of colorectal cancer biomarkers

K Wang, C Huang, EC Nice - Expert review of proteomics, 2014 - Taylor & Francis
Colorectal cancer (CRC) is the second most common cancer in females and the third in
males. Since CRC is often diagnosed at an advanced stage when prognosis is poor …

Multi-omic approaches in colorectal cancer beyond genomic data

E Sardo, S Napolitano, CM Della Corte… - Journal of Personalized …, 2022 - mdpi.com
Colorectal cancer (CRC) is one of the most frequent tumours and one of the major causes of
morbidity and mortality globally. Its incidence has increased in recent years and could be …

High-throughput omics and statistical learning integration for the discovery and validation of novel diagnostic signatures in colorectal cancer

NP Long, S Park, NH Anh, TD Nghi, SJ Yoon… - International journal of …, 2019 - mdpi.com
The advancement of bioinformatics and machine learning has facilitated the discovery and
validation of omics-based biomarkers. This study employed a novel approach combining …

[HTML][HTML] Omics technologies for improved diagnosis and treatment of colorectal cancer: Technical advancement and major perspectives

N Dalal, R Jalandra, M Sharma, H Prakash… - Biomedicine & …, 2020 - Elsevier
Colorectal cancer (CRC) ranks third among the most commonly occurring cancers
worldwide, and it causes half a million deaths annually. Alongside mechanistic study for …

Biomarkers in colorectal cancer: the role of translational proteomics research

BA Alves Martins, GF de Bulhoes, IN Cavalcanti… - Frontiers in …, 2019 - frontiersin.org
Colorectal cancer is one of the most common cancers in the world, and it is one of the
leading causes of cancer-related death. Despite recent progress in the development of …

[HTML][HTML] Biomarkers in colorectal cancer: the role of translational proteomics research

BAA Martins, GF De Bulhões, IN Cavalcanti… - Frontiers in …, 2019 - ncbi.nlm.nih.gov
Colorectal cancer is one of the most common cancers in the world, and it is one of the
leading causes of cancer-related death. Despite recent progress in the development of …