Organoids have emerged as a powerful tool for understanding the biology of the respiratory,
digestive, nervous as well as urinary system, investigating infections, and developing new …

Traditionally, human virus research has relied on results generated from immortalized cell
lines and animal models experiments. For new (antiviral) drugs to become available on the …

Infectious diseases worldwide affect human health and have important societal impacts. A
better understanding of infectious diseases is urgently needed. In vitro and in vivo infection …

To study the host–pathogen interactions with medical and veterinary relevance, researchers
have recently applied organoid technology. Organoids revolutionized biomedical research …

To adequately prepare against imminent disease outbreaks from diverse and ever-changing
viral pathogens, improved experimental models that can accurately recapitulate host-virus …

Animal models and cell lines are invaluable for virology research and host–pathogen
interaction studies. However, it is increasingly evident that these models are not sufficient to …

Organoid is an in vitro multicellular form mimicking in vivo organ. Its similarity to human
organ including cellular organization, molecular expression patterns, as well as genetic …

The escalation of antibiotic resistance, pandemics, and nosocomial infections underscores
the importance of research in both animal and human infectious diseases. Recent …

Viral pathogens utilize various human organs for infection, and the gut is one of the primary
entry sites for the viral pathogen. The gut epithelium is tightly maintained since multiple …

Infectious diseases are a major threat worldwide. With the alarming rise of antimicrobial
resistance and emergence of new potential pathogens, a better understanding of the …