Inflammation represents the driving feature of many diseases, including atherosclerosis,
cancer, autoimmunity and infections. It is now established that metabolic processes shape a …

The immune system protects the body against harm by inducing inflammation. During the
immune response, cells of the immune system get activated, divided and differentiated in …

Cholesterol, the most important sterol in mammals, helps maintain plasma membrane fluidity
and is a precursor of bile acids, oxysterols, and steroid hormones. Cholesterol in the body is …

Hypercholesterolaemia leads to cholesterol accumulation in macrophages and other
immune cells, which promotes inflammatory responses, including augmentation of Toll-like …

Abstract Purpose of Review Atherosclerosis is an inflammatory disorder of the arterial wall,
in which several players contribute to the onset and progression of the disease. Besides the …

It has been long recognized that cholesterol is a critical molecule in mammalian cell biology,
primarily for its contribution to the plasma membrane's composition and its role in assuring …

Atherosclerosis is a common cardiovascular disease caused by the abnormal expression of
multiple factors and genes influenced by both environmental and genetic factors. The …

Metabolic conditions such as obesity and associated comorbidities are increasing in
prevalence worldwide. In chronically inflamed pathologies, metabolic conditions are linked …

The causal role of inflammation at the core of endothelial dysfunction, atherosclerosis and
cardiovascular diseases is discussed. Atherosclerosis is an arterial disease characterized …

Cardiovascular disease (CVD) continues to be a leading cause of death worldwide with
atherosclerosis being the major underlying pathology. The interplay between lipids and …