Triazole derivatives and their antiplasmodial and antimalarial activities

XM Chu, C Wang, WL Wang, LL Liang, W Liu… - European journal of …, 2019 - Elsevier
Malaria, caused by protozoan parasites of the genus Plasmodium especially by the most
prevalent parasite Plasmodium falciparum, represents one of the most devastating and …

Current development of 1, 2, 3-triazole derived potential antimalarial scaffolds: Structure activity relationship (SAR) and bioactive compounds

SMA Rahman, JS Bhatti, S Thareja, V Monga - European Journal of …, 2023 - Elsevier
Malaria is among one of the most devastating and deadliest parasitic disease in the world
claiming millions of lives every year around the globe. It is a mosquito-borne infectious …

Triazole hybrid compounds: A new frontier in malaria treatment

L Ravindar, SA Hasbullah, KP Rakesh… - European Journal of …, 2023 - Elsevier
Reviewing the advancements in malaria treatment, the emergence of triazole hybrid
compounds stands out as a groundbreaking development. Combining the advantages of …

Recent advances and future perspectives of triazole analogs as promising antiviral agents

R Kharb, M Shahar Yar… - Mini reviews in …, 2011 - ingentaconnect.com
Emergence of severe viral infections in recent years and limited availability of antiviral
chemotherapeutic agents for prevention and treatment of these infections are among the …

New Compounds Hybrids 1H‐1,2,3‐Triazole‐Quinoline Against Plasmodium falciparum

N Boechat, MLG Ferreira, LCS Pinheiro… - Chemical Biology & …, 2014 - Wiley Online Library
Malaria is one of the most prevalent parasitic diseases in the world. The global importance
of this disease, current vector control limitations, and the absence of an effective vaccine …

Synthesis of 4‐aminoquinoline‐1, 2, 3‐triazole and 4‐aminoquinoline‐1, 2, 3‐triazole‐1, 3, 5‐triazine Hybrids as Potential Antimalarial Agents

S Manohar, SI Khan, DS Rawat - Chemical Biology & Drug …, 2011 - Wiley Online Library
We report herein synthesis of a series of 4‐aminoquinoline‐1, 2, 3‐triazole and 4‐
aminoquinoline‐1, 2, 3‐triazole‐1, 3, 5‐triazine hybrids and evaluate their antimalarial …

Recent researches in triazole compounds as medicinal drugs

CH Zhou, Y Wang - Current medicinal chemistry, 2012 - ingentaconnect.com
Triazole compounds containing three nitrogen atoms in the five-membered aromatic azole
ring are readily able to bind with a variety of enzymes and receptors in biological system via …

Triazoles and their derivatives: Chemistry, synthesis, and therapeutic applications

MM Matin, P Matin, MR Rahman… - Frontiers in molecular …, 2022 - frontiersin.org
Among the nitrogen-containing heterocyclic compounds, triazoles emerge with superior
pharmacological applications. Structurally, there are two types of five-membered triazoles: 1 …

[HTML][HTML] Pyrazole and pyrazoline derivatives as antimalarial agents: A key review

L Ravindar, SA Hasbullah, KP Rakesh… - European Journal of …, 2023 - Elsevier
Malaria poses a severe public health risk and a significant economic burden in disease-
endemic countries. One of the most severe issues in malaria control is the development of …

New heterocyclic hybrids of pyrazole and its bioisosteres: Design, synthesis and biological evaluation as dual acting antimalarial-antileishmanial agents

AA Bekhit, AMM Hassan, HA Abd El Razik… - European journal of …, 2015 - Elsevier
A new series of pyrazole derivatives were synthesized by hybridization with five-membered
heterocyclic moieties such as thiazoles, thiazolidinones, 1, 3, 4-thiadiazoles and …