The combination of CXCL9, CXCL10 and CXCL11 levels during primary HIV infection predicts HIV disease progression
X Yin, Z Wang, T Wu, M Ma, Z Zhang, Z Chu… - Journal of Translational …, 2019 - Springer
Background Chemokines are small chemotactic cytokines involved in inflammation, cell
migration, and immune regulation in both physiological and pathological contexts. Here, we …
migration, and immune regulation in both physiological and pathological contexts. Here, we …
CXCL16 in HIV infection–a link between inflammation and viral replication
L Landrø, JK Damås, B Halvorsen… - European journal of …, 2009 - Wiley Online Library
Background While some chemokines are thought to be protective in HIV‐infected individuals
by their ability to block HIV entry into T cells and macrophages, chemokines could also have …
by their ability to block HIV entry into T cells and macrophages, chemokines could also have …
CXCL13 as a biomarker of immune activation during early and chronic HIV infection
Background: CXCL13 is preferentially secreted by Follicular Helper T cells (TFH) to attract B
cells to germinal centers. Plasma levels of CXCL13 have been reported to be elevated …
cells to germinal centers. Plasma levels of CXCL13 have been reported to be elevated …
High CXCL10/IP-10 levels are a hallmark in the clinical evolution of the HIV infection
JM Valverde-Villegas, RM de Medeiros… - Infection, Genetics and …, 2018 - Elsevier
The aim of this study was to investigate the modulation of plasma CXCL10, CCL20, CCL22,
CCL2, CCL17 and CCL24 levels in HIV-positive patients grouped according to extreme …
CCL2, CCL17 and CCL24 levels in HIV-positive patients grouped according to extreme …
High circulating SDF-1and MCP-1 levels and genetic variations in CXCL12, CCL2 and CCR5: Prognostic signature of immune recovery status in treated HIV-positive …
E Yeregui, C Viladés, P Domingo, A Ceausu… - …, 2020 - thelancet.com
Background The underlying mechanisms of incomplete immune reconstitution in treated HIV-
positive patients are very complex and may be multifactorial, but perturbation of chemokine …
positive patients are very complex and may be multifactorial, but perturbation of chemokine …
Chemokine CXCL8 Promotes HIV-1 Replication in Human Monocyte-Derived Macrophages and Primary Microglia via Nuclear Factor-κB Pathway
MK Mamik, A Ghorpade - PloS one, 2014 - journals.plos.org
Background Chemokine CXCL8 is an important neutrophil chemoattractant implicated in
various neurodegenerative disorders. Cytokine/chemokine imbalance, with an increase in …
various neurodegenerative disorders. Cytokine/chemokine imbalance, with an increase in …
High plasma CXCL10 levels are associated with HCV-genotype 1, and higher insulin resistance, fibrosis, and HIV viral load in HIV/HCV coinfected patients
J Berenguer, A Fernandez-Rodríguez… - Cytokine, 2012 - Elsevier
BACKGROUND: CXCL10 may contribute to the host immune response against the hepatitis
C virus (HCV), liver disease progression, and response to HCV antiviral therapy. The aim of …
C virus (HCV), liver disease progression, and response to HCV antiviral therapy. The aim of …
Plasma CXCL10 correlates with HAND in HIV-infected women
R Burlacu, A Umlauf, TD Marcotte… - Journal of …, 2020 - Springer
HIV-associated neurocognitive disorder (HAND) is characterized by chronic immune
activation. We aimed to identify biomarkers associated with HAND and to investigate their …
activation. We aimed to identify biomarkers associated with HAND and to investigate their …
Selective Expansion of Pro-inflammatory Chemokine CCL2-Loaded CD14+CD16+ Monocytes Subset in HIV-Infected Therapy Naïve Individuals
AW Ansari, D Meyer-Olson, RE Schmidt - Journal of clinical immunology, 2013 - Springer
We have previously demonstrated the critical role of CC chemokine CCL2 in HIV-1
pathogenesis, and circulating monocytes as the major source of CCL2. Since the functional …
pathogenesis, and circulating monocytes as the major source of CCL2. Since the functional …
Cerebrospinal fluid CXCL13 as candidate biomarker of intrathecal immune activation, IgG synthesis and neurocognitive impairment in people with HIV
M Trunfio, L Mighetto, L Napoli, C Atzori… - Journal of Neuroimmune …, 2023 - Springer
Plasma CXC-motif chemokine ligand-13 (CXCL13) has been linked to disease progression
and mortality in people living with HIV (PLWH) and is a candidate target for immune-based …
and mortality in people living with HIV (PLWH) and is a candidate target for immune-based …