[HTML][HTML] Male factor subfertility: possible causes and the impact of nutritional factors

WY Wong, CMG Thomas, JMWM Merkus, GA Zielhuis… - Fertility and sterility, 2000 - Elsevier
Objective: To review possible causes for male factor subfertility with emphasis on nutritional
factors such as zinc and folate. Design: A literature search was performed on MEDLINE and …

[HTML][HTML] Effects of folic acid and zinc sulfate on male factor subfertility: a double-blind, randomized, placebo-controlled trial

WY Wong, HMWM Merkus, CMG Thomas… - Fertility and sterility, 2002 - Elsevier
Objective: To study the effects of folic acid and zinc sulfate treatment on semen variables in
fertile and subfertile men. Design: Double-blind, placebo-controlled interventional study …

The importance of folate, zinc and antioxidants in the pathogenesis and prevention of subfertility

IMW Ebisch, CMG Thomas, WHM Peters… - Human reproduction …, 2007 - academic.oup.com
Current treatments of subfertile couples are usually empiric, as the true cause of subfertility
often remains unknown. Therefore, we outline the role of nutritional and biochemical factors …

Does folic acid and zinc sulphate intervention affect endocrine parameters and sperm characteristics in men?

IMW Ebisch, FH Pierik, FH De Jong… - … journal of andrology, 2006 - Wiley Online Library
We evaluated pre‐and post‐intervention endocrine and semen parameters in a double‐
blind, placebo‐controlled intervention study to investigate the underlying mechanism of …

[HTML][HTML] The genetic causes of male factor infertility: a review

KLO O'brien, AC Varghese, A Agarwal - Fertility and sterility, 2010 - Elsevier
OBJECTIVE: To illustrate the necessity for an enhanced understanding of the genetic basis
of male factor infertility, to present a comprehensive synopsis of these genetic elements, and …

Iron and copper in male reproduction: a double-edged sword

E Tvrda, R Peer, SC Sikka, A Agarwal - Journal of assisted reproduction …, 2015 - Springer
Iron and copper are essential trace nutrients playing important roles in general health and
fertility. However, both elements are highly toxic when accumulating in large quantities …

[HTML][HTML] Trends of male factor infertility, an important cause of infertility: A review of literature

N Kumar, AK Singh - Journal of human reproductive sciences, 2015 - journals.lww.com
Infertility and problems of impaired fecundity have been a concern through ages and is also
a significant clinical problem today, which affects 8–12% of couples worldwide. Of all …

[HTML][HTML] Zinc is an essential element for male fertility: a review of Zn roles in men's health, germination, sperm quality, and fertilization

A Fallah, A Mohammad-Hasani… - Journal of reproduction & …, 2018 - ncbi.nlm.nih.gov
Zinc (Zn) is the second most abundant trace element in human, which can't be stored in the
body, thus regular dietary intake is required. This review explained the physiological and …

The effect of folate and folate plus zinc supplementation on endocrine parameters and sperm characteristics in sub-fertile men: a systematic review and meta-analysis

M Irani, M Amirian, R Sadeghi, J Le Lez… - Urology journal, 2017 - ojs3.sbmu.ac.ir
Purpose: To evaluate the effect of folate and folate plus zinc supplementation on endocrine
parameters and sperm characteristics in sub fertile men. Materials and Methods: We …

Zinc levels in seminal plasma are associated with sperm quality in fertile and infertile men

AH Colagar, ET Marzony, MJ Chaichi - Nutrition research, 2009 - Elsevier
Zinc has antioxidative properties and plays an important role in scavenging reactive oxygen
species. We hypothesized that in the absence of Zn, the possibility of increased oxidative …