Cancer often develops multidrug resistance (MDR) when cancer cells become resistant to
numerous structurally and functionally different chemotherapeutic agents. MDR is …

Chemotherapy remains a powerful tool to eliminate malignant cells. However, the efficacy of
chemotherapy is compromised by the frequent emergence of intrinsic and acquired …

Drug resistance is the most significant causes of cancer chemotherapy failure. Various
mechanisms of drug resistance include tumor heterogeneity, tumor microenvironment …

Cancer is one of the leading causes of morbidity and mortality around the globe and is likely
to become the major cause of global death in the coming years. As per World Health …

Chemotherapy typically involves the use of specific chemodrugs to inhibit the proliferation of
cancer cells, but the frequent emergence of a variety of multidrug‐resistant cancer cells …

Different mechanisms in cancer cells become resistant to one or more chemotherapeutics is
known as multidrug resistance (MDR) which hinders chemotherapy efficacy. Potential …

Cancer remains a major killer of mankind. Failure of conventional chemotherapy has
resulted in recurrence and development of virulent multi drug resistant (MDR) phenotypes …

Multidrug resistance (MDR) is one of the key barriers in chemotherapy, leading to the
generation of insensitive cancer cells towards administered therapy. Genetic and epigenetic …

Multidrug resistance (MDR) of tumors is one of the clinical direct reasons for chemotherapy
failure. MDR directly leads to tumor recurrence and metastasis, with extremely grievous …

Cancer is currently one of the most intractable diseases causing human death. Although the
prognosis of tumor patients has been improved to a certain extent through various modern …