Quantification of the biological age of the brain using neuroimaging

JH Cole, K Franke, N Cherbuin - Biomarkers of human aging, 2019 - Springer
The cosmetic and behavioural aspects of ageing become increasingly apparent with the
passing years. The individual variability in physical ageing can be immediately observed in …

Predicting age using neuroimaging: innovative brain ageing biomarkers

JH Cole, K Franke - Trends in neurosciences, 2017 - cell.com
The brain changes as we age and these changes are associated with functional
deterioration and neurodegenerative disease. It is vital that we better understand individual …

Ten Years of BrainAGE as a Neuroimaging Biomarker of Brain Aging: What Insights Have We Gained?

K Franke, C Gaser - Frontiers in neurology, 2019 - frontiersin.org
With the aging population, prevalence of neurodegenerative diseases is increasing, thus
placing a growing burden on individuals and the whole society. However, individual rates of …

[HTML][HTML] Neuroimaging-derived brain-age: an ageing biomarker?

JH Cole - Aging (Albany NY), 2017 - ncbi.nlm.nih.gov
James H. Cole www. aging-us. com AGING 2017, Vol. 9, No. 8 www. aging-us. com 1861
AGING the context of non-pathological ageing, this satisfies criteria# 2. As a non-invasive …

Individual variations in 'brain age'relate to early-life factors more than to longitudinal brain change

D Vidal-Pineiro, Y Wang, SK Krogsrud, IK Amlien… - elife, 2021 - elifesciences.org
Brain age is a widely used index for quantifying individuals' brain health as deviation from a
normative brain aging trajectory. Higher-than-expected brain age is thought partially to …

Brain age and other bodily 'ages': implications for neuropsychiatry

JH Cole, RE Marioni, SE Harris, IJ Deary - Molecular psychiatry, 2019 - nature.com
As our brains age, we tend to experience cognitive decline and are at greater risk of
neurodegenerative disease and dementia. Symptoms of chronic neuropsychiatric diseases …

Brain age predicts mortality

JH Cole, SJ Ritchie, ME Bastin, V Hernández… - Molecular …, 2018 - nature.com
Age-associated disease and disability are placing a growing burden on society. However,
ageing does not affect people uniformly. Hence, markers of the underlying biological ageing …

Clinical neurophysiology of aging brain: from normal aging to neurodegeneration

PM Rossini, S Rossi, C Babiloni, J Polich - Progress in neurobiology, 2007 - Elsevier
Physiological brain aging is characterized by a loss of synaptic contacts and neuronal
apoptosis that provokes age-dependant decline of sensory processing, motor performance …

[HTML][HTML] Trajectories of imaging markers in brain aging: the Rotterdam Study

EJ Vinke, M de Groot, V Venkatraghavan, S Klein… - Neurobiology of …, 2018 - Elsevier
With aging, the brain undergoes several structural changes. These changes reflect the
normal aging process and are therefore not necessarily pathologic. In fact, better …

Healthy and pathological processes in adult development: new evidence from neuroimaging of the aging brain

T Hedden, JDE Gabrieli - Current opinion in neurology, 2005 - journals.lww.com
Healthy and pathological processes in adult development: new... : Current Opinion in
Neurology Healthy and pathological processes in adult development: new evidence from …