Brain morphologic changes in early stages of psychosis: implications for clinical application and early intervention
T Takahashi, M Suzuki - Psychiatry and clinical neurosciences, 2018 - Wiley Online Library
To date, a large number of magnetic resonance imaging (MRI) studies have been conducted
in schizophrenia, which generally demonstrate gray matter reduction, predominantly in the …
in schizophrenia, which generally demonstrate gray matter reduction, predominantly in the …
Progressive structural brain abnormalities and their relationship to clinical outcome: a longitudinal magnetic resonance imaging study early in schizophrenia
BC Ho, NC Andreasen, P Nopoulos… - Archives of general …, 2003 - jamanetwork.com
Background Many studies have shown that structural brain abnormalities in schizophrenia
are already present by the time of index evaluation of first-episode patients. However …
are already present by the time of index evaluation of first-episode patients. However …
Gray matter volumetric abnormalities associated with the onset of psychosis
Patients with psychosis display structural brain abnormalities in multiple brain regions. The
disorder is characterized by a putative prodromal period called ultra-high-risk (UHR) status …
disorder is characterized by a putative prodromal period called ultra-high-risk (UHR) status …
Brain imaging during the transition from psychosis prodrome to schizophrenia
Neuroimaging studies have identified patterns of brain abnormalities in various stages of
schizophrenia, but whether these abnormalities reflect primary factors associated with the …
schizophrenia, but whether these abnormalities reflect primary factors associated with the …
A selective review of cerebral abnormalities in patients with first-episode schizophrenia before and after treatment
Q Gong, S Lui, JA Sweeney - American Journal of Psychiatry, 2016 - Am Psychiatric Assoc
The question of whether there are significant changes in brain anatomy and function at
illness onset and over the early course of schizophrenia is a crucial issue with broad …
illness onset and over the early course of schizophrenia is a crucial issue with broad …
Mapping prodromal psychosis: a critical review of neuroimaging studies
P Fusar-Poli, P McGuire, S Borgwardt - European Psychiatry, 2012 - cambridge.org
The onset of schizophrenia is usually preceded by a prodromal phase characterized by
functional decline and subtle prodromal symptoms, which include attenuated psychotic …
functional decline and subtle prodromal symptoms, which include attenuated psychotic …
Lack of progression of brain abnormalities in first-episode psychosis: a longitudinal magnetic resonance imaging study
BackgroundSome neuroimaging studies have supported the hypothesis of progressive brain
changes after a first episode of psychosis. We aimed to determine whether (i) first-episode …
changes after a first episode of psychosis. We aimed to determine whether (i) first-episode …
Brain morphology in first-episode schizophrenic-like psychotic patients: a quantitative magnetic resonance imaging study
LE DeLisi, AL Hoff, JE Schwartz, GW Shields… - Biological …, 1991 - Elsevier
Brain morphology was examined using magnetic resonance imaging in 30 first-episode
patients with a schizophreniclike psychosis, 15 chronic schizophenics, and 20 neurological …
patients with a schizophreniclike psychosis, 15 chronic schizophenics, and 20 neurological …
Structural brain changes in schizophrenia at different stages of the illness: a selective review of longitudinal magnetic resonance imaging studies
B Dietsche, T Kircher… - Australian & New Zealand …, 2017 - journals.sagepub.com
Objective: Schizophrenia is a devastating mental disorder accompanied by aberrant
structural brain connectivity. The question whether schizophrenia is a progressive brain …
structural brain connectivity. The question whether schizophrenia is a progressive brain …
Structural brain imaging evidence for multiple pathological processes at different stages of brain development in schizophrenia
The underlying neurobiology of emerging psychotic disorders is not well understood. While
there is evidence from structural imaging and other studies supporting the popular notion …
there is evidence from structural imaging and other studies supporting the popular notion …