Maintaining blood glucose at an appropriate physiological level requires precise
coordination of multiple organs and tissues. The vagus nerve bidirectionally connects the …

Glucose sensing within autonomic neurocircuits is critical for the effective integration and
regulation of a variety of physiological homeostatic functions including the co-ordination of …

Neurons in the brain stem dorsal vagal complex (DVC) take part in a continuous
bidirectional crosstalk, in which they receive and respond to a vast array of signaling …

The regulation of energy and glucose balance contributes to whole-body metabolic
homeostasis, and such metabolic regulation is disrupted in obesity and diabetes. Metabolic …

Although it is generally acknowledged that pancreatic islets are under powerful vagal
control, specifics of vagal pathways and their central representation in the brain stem are …

Maintenance of glucose homeostasis is mandatory for organismal survival. It is
accomplished by complex and coordinated interplay between glucose detection …

Glucose homeostasis is mainly under the control of the pancreatic islet hormones insulin
and glucagon, which, respectively, stimulate glucose uptake and utilization by liver, fat, and …

Background Glucose is a crucial energy source. In humans, it is the primary sugar for high
energy demanding cells in brain, muscle and peripheral neurons. Deviations of blood …

These recent findings demonstrate that the use of improved anatomical and physiological
techniques and animal models with targeted gene modifications lead to an improved …

Sensory neurons relay gut-derived signals to the brain, yet the molecular and functional
organization of distinct populations remains unclear. Here, we employed intersectional …