Sperm DNA damage is a useful biomarker for male infertility diagnosis and prediction of
assisted reproduction outcomes. It is associated with reduced fertilization rates, embryo …

Assessments of sperm DNA damage are controversial because of perceived uncertainties
over the relationship with pregnancy and the limited range of therapies available should …

While the semen analysis has traditionally been relied upon to differentiate fertile and
infertile men, its utility has been questioned in the current era of assisted reproductive …

DNA fragmentation is an important factor in the aetiology of male infertility. However, it is still
underevaluated and its inclusion in routine semen analysis is debated. DNA fragmentation …

DNA damage in the male germ line has been associated with poor semen quality, low
fertilization rates, impaired preimplantation development, increased abortion and an …

Sperm DNA contributes half the offspring's genomic material and abnormal DNA can lead to
derangements in the reproductive process. Normal sperm genetic material is required for …

DNA damage is a common feature of human spermatozoa with purported links to poor rates
of conception, impaired embryonic development, an increased incidence of miscarriage and …

Male factor is responsible for up to 50% of infertility cases in the world. Semen analysis is
considered the cornerstone of laboratory evaluation of male infertility, but it has its own …

Reproductive diseases have become a growing worldwide problem and male factor plays
an important role in the reproductive diagnosis, prognosis and design of assisted …

There now exists clinical evidence to show that sperm DNA damage is detrimental to
reproductive outcomes. Tests for DNA damage may provide better prognostic information …