Ambient air pollution and atherosclerosis: a potential mediating role of sphingolipids

Y Xu, Y Han, Y Wang, J Gong, H Li… - … and Vascular Biology, 2022 - Am Heart Assoc
Background: The pathophysiological mechanisms of air pollution-induced atherosclerosis
are incompletely understood. Sphingolipids serve as biological intermediates during …

Pro-inflammation and pro-atherosclerotic responses to short-term air pollution exposure associated with alterations in sphingolipid ceramides and neutrophil …

Y Zhu, H Xu, T Wang, Y Xie, L Liu, X He, C Liu… - Environmental …, 2023 - Elsevier
Air pollution has been associated with the development of atherosclerosis; however, the
pathophysiological mechanisms underlying pro-atherosclerotic effects of air pollution …

Particulate air pollution and clinical cardiovascular disease risk factors

RP Shanley, RB Hayes, KR Cromar, K Ito… - …, 2016 - journals.lww.com
Background: Long-term exposure to ambient particulate matter (PM) air pollution is
associated with increased cardiovascular disease (CVD); however, the impact of PM on …

Extreme levels of air pollution associated with changes in biomarkers of atherosclerotic plaque vulnerability and thrombogenicity in healthy adults: the Beijing AIRCHD …

H Xu, T Wang, S Liu, RD Brook, B Feng… - Circulation …, 2019 - Am Heart Assoc
Rationale: The pathophysiologic mechanisms of air pollution–associated exacerbation of
cardiovascular events remain incompletely understood. Objective: To assess whether …

Plasma sphingolipids and risk of cardiovascular diseases: a large-scale lipidomic analysis

JYH Seah, WS Chew, F Torta, CM Khoo, MR Wenk… - Metabolomics, 2020 - Springer
Introduction Sphingolipids are a diverse class of lipids with various roles in cell functions
and subclasses such as ceramides have been associated with cardiovascular diseases …

Ambient air pollution and atherosclerosis: recent updates

GH Bevan, SG Al-Kindi, R Brook… - Current atherosclerosis …, 2021 - Springer
Abstract Purpose of Review During the past century, exposure to particulate matter (PM) air
pollution< 2.5 μm in diameter (PM2. 5) has emerged as an all-pervading element of modern …

Fine particulate matter air pollution and atherosclerosis: mechanistic insights

Y Bai, Q Sun - Biochimica et Biophysica Acta (BBA)-General Subjects, 2016 - Elsevier
Background Atherosclerosis is a progressive disease characterized by the accumulation of
lipids and fibrous plaque in the arteries. Its etiology is very complicated and its risk factors …

[HTML][HTML] The mediation effect of lipids, blood pressure and BMI between air pollutant mixture and atherosclerotic cardiovascular disease: the CHCN-BTH cohort study

B Li, F Wen, K Liu, Y Xie, F Zhang, P Li, Y Sun… - Ecotoxicology and …, 2023 - Elsevier
Highlights•Air pollutant mixture were associated with ASCVD incidence, especially IHD.•The
main impact component of air pollutant mixture to ASCVD is PM 2.5.•The effect of OM to …

Association of air pollution exposures with high-density lipoprotein cholesterol and particle number: the multi-ethnic study of atherosclerosis

G Bell, S Mora, P Greenland, M Tsai, E Gill… - … , and vascular biology, 2017 - Am Heart Assoc
Objective—The relationship between air pollution and cardiovascular disease may be
explained by changes in high-density lipoprotein (HDL). Approach and Results—We …

Fine particulate matter (PM2.5) inhalation-induced alterations in the plasma lipidome as promoters of vascular inflammation and insulin resistance

BG Hill, B Rood, A Ribble… - American Journal of …, 2021 - journals.physiology.org
Fine particulate matter (PM2. 5) air pollution exposure increases the risk of developing
cardiovascular disease (CVD). Although the precise mechanisms by which air pollution …