Glioblastoma multiforme (GBM) is the most common primary brain tumour in adults and one
of the most aggressive cancers in man. Despite technological advances in surgical …

Malignant gliomas are characterized by an intrinsic resistance to apoptosis. Increasing
evidence suggests that this is a fundamental mechanism by which gliomas evade …

The treatment of glioblastoma remains a major challenge for clinicians since these highly
aggressive brain tumors are relatively resistant towards radio-and chemotherapy. The …

Glioblastoma multiforme (GBM) is the most hostile type of brain cancer. Its aggressiveness is
due to increased invasion, migration, proliferation, angiogenesis, and a decreased …

Glioblastoma (GBM) is the most common and lethal tumor of the central nervous system. The
natural history of treated GBM remains very poor with 5-year survival rates of 5%. Survival …

Understanding apoptosis is often considered a key to understand the genesis of tumors and
to devise innovative strategies for their treatment. Similar to other types of cancer, essential …

Glioblastoma multiforme (GBM) is the most malignant and aggressive type of brain tumor
with an average life expectancy of less than 15 months. This is mostly due to the highly …

Cells of glioblastoma, the most frequent primary malignant brain tumor, are characterized by
their rapid growth and infiltration of adjacent healthy brain parenchyma, which reflects their …

Neuroblastoma is a pediatric solid tumor with high morbidity and mortality in association with
particular high-risk biological and clinical features (such as MYCN proto-oncogene …

Glioblastoma multiforme (GBM), a WHO grade IV malignant glioma, is the most common and
lethal primary brain tumor in adults; few treatments are available. Median survival rates …