Stem cell-based therapies for the treatment of stroke have received considerable attention.
Two broad approaches to stem cell-based therapies have been taken: the transplantation of …

Stroke can lead to long-term neurological deficits. Adult neurogenesis, the continuous
generation of newborn neurons in distinct regions of the brain throughout life, has been …

Stroke causes a devastating insult to the brain resulting in severe neurological deficits
because of a massive loss of different neurons and glia. In the United States, stroke is the …

No effective therapy is currently available to promote recovery following ischemic stroke.
Stem cells have been proposed as a potential source of new cells to replace those lost due …

Cell therapy holds great promise for regenerative treatment of disease. Despite recent
breakthroughs in clinical research, applications of cell therapies to the injured brain have not …

Acute injuries to CNS such as stroke induce neural progenitor proliferation in adult brain
which might be an endogenous attempt to self-repair. This process is known to be altered by …

Current treatments for stroke, such as the use of thrombolytic agents, are often limited by a
narrow therapeutic time window. However, the regeneration of the brain after damage is still …

In ischemic stroke, the third most frequent cause of mortality in industrialized countries,
therapeutic options have until now been limited to the first hours after disease onset. Cell …

Stem cells exert therapeutic effects against ischemic stroke via transplantation of exogenous
stem cells or stimulation of endogenous stem cells within the neurogenic niches of …

Stroke remains a prevalent disease with limited treatment options. Available treatments offer
little in the way of enhancing neurogenesis and recovery. Because of the limitations of …