Importance The Third International Consensus Definitions Task Force defined sepsis as “life-
threatening organ dysfunction due to a dysregulated host response to infection.” The …

Importance Definitions of sepsis and septic shock were last revised in 2001. Considerable
advances have since been made into the pathobiology (changes in organ function …

Over the past 30 years, 2 major factors have led to a perceived need for better definitions. In
particular, the increasing sophistication, at least in high-income countries, of modalities …

CMAJ| SEPTEMBER 10, 2018| VoluME 190| ISSuE 36 E1059 in Sepsis-3 indicates severe
illness; it is not clinically equivalent to a screening test (ie, a trigger for the start of treatment) …

Importance An international task force recently redefined the concept of sepsis. This task
force recommended the use of the quick Sequential Organ Failure Assessment (qSOFA) …

Summary Background The Third International Consensus Definitions for Sepsis and Septic
Shock (Sepsis-3) present clinical criteria for the classification of patients with sepsis. We …

© Journal of Thoracic Disease. All rights reserved. J Thorac Dis 2017; 9 (4): 943-945 jtd.
amegroups. com of data collection for clinical trials in the intensive care unit (ICU). However …

Sepsis is responsible for the utilisation of a significant proportion of healthcare resources
and has high mortality rates. Early diagnosis and prompt interventions are associated with …

Objectives Sepsis-3 definitions generated controversies regarding their general
applicability. The Sepsis-3 Task Force outlined the need for validation with emphasis on the …

Sepsis is a major cause of death, disability, and cost to the health care system. However,
despite its clinical significance, sepsis is difficult to define. For more than 2 decades, the …