[HTML][HTML] CpG and non-CpG methylation in epigenetic gene regulation and brain function
HS Jang, WJ Shin, JE Lee, JT Do - Genes, 2017 - mdpi.com
DNA methylation is a major epigenetic mark with important roles in genetic regulation.
Methylated cytosines are found primarily at CpG dinucleotides, but are also found at non …
Methylated cytosines are found primarily at CpG dinucleotides, but are also found at non …
[HTML][HTML] Mammalian non-CpG methylation: stem cells and beyond
SE Pinney - Biology, 2014 - mdpi.com
Although CpG dinucleotides remain the primary site for DNA methylation in mammals, there
is emerging evidence that DNA methylation at non-CpG sites (CpA, CpT and CpC) is not …
is emerging evidence that DNA methylation at non-CpG sites (CpA, CpT and CpC) is not …
Distribution, recognition and regulation of non-CpG methylation in the adult mammalian brain
DNA methylation has critical roles in the nervous system and has been traditionally
considered to be restricted to CpG dinucleotides in metazoan genomes. Here we show that …
considered to be restricted to CpG dinucleotides in metazoan genomes. Here we show that …
The evidence for functional non-CpG methylation in mammalian cells
In mammalian genomes, the methylation of cytosine residues within CpG dinucleotides is
crucial to normal development and cell differentiation. However, methylation of cytosines in …
crucial to normal development and cell differentiation. However, methylation of cytosines in …
[HTML][HTML] Genomic distribution and inter-sample variation of non-CpG methylation across human cell types
DNA methylation plays an important role in development and disease. The primary sites of
DNA methylation in vertebrates are cytosines in the CpG dinucleotide context, which …
DNA methylation in vertebrates are cytosines in the CpG dinucleotide context, which …
Differences in DNA methylation between human neuronal and glial cells are concentrated in enhancers and non-CpG sites
A Kozlenkov, P Roussos, A Timashpolsky… - Nucleic acids …, 2014 - academic.oup.com
Abstract We applied Illumina Human Methylation450K array to perform a genomic-scale
single-site resolution DNA methylation analysis in neuronal and nonneuronal (primarily …
single-site resolution DNA methylation analysis in neuronal and nonneuronal (primarily …
The emergence of the brain non-CpG methylation system in vertebrates
Mammalian brains feature exceptionally high levels of non-CpG DNA methylation alongside
the canonical form of CpG methylation. Non-CpG methylation plays a critical regulatory role …
the canonical form of CpG methylation. Non-CpG methylation plays a critical regulatory role …
Reading the unique DNA methylation landscape of the brain: Non-CpG methylation, hydroxymethylation, and MeCP2
DNA methylation at CpG dinucleotides is an important epigenetic regulator common to
virtually all mammalian cell types, but recent evidence indicates that during early postnatal …
virtually all mammalian cell types, but recent evidence indicates that during early postnatal …
CpG methylation recruits sequence specific transcription factors essential for tissue specific gene expression
R Chatterjee, C Vinson - Biochimica et Biophysica Acta (BBA)-Gene …, 2012 - Elsevier
CG methylation is an epigenetically inherited chemical modification of DNA found in plants
and animals. In mammals it is essential for accurate regulation of gene expression and …
and animals. In mammals it is essential for accurate regulation of gene expression and …
Non-CG methylation in the human genome
DNA methylation is a chemical modification that occurs predominantly on CG dinucleotides
in mammalian genomes. However, recent studies have revealed that non-CG methylation …
in mammalian genomes. However, recent studies have revealed that non-CG methylation …