Background Modulation of pain perception by oxytocin (OXT) has attracted increased
scientific and clinical interest. Neural mechanisms underlying these effects are poorly …

Study Design. The effect of oxytocin on low back pain in patients and its mechanism in rats
were investigated. Methods. Intrathecal injection, radioimmunoassay, and potassium …

The neuropeptide oxytocin (OT) has been shown to play a modulatory role in nociception.
However, analgesic effects of OT in chronic pain conditions remain elusive and the neural …

Background There is increasing evidence for oxytocin as a neurotransmitter in spinal
nociceptive processes. Hypothalamic oxytocinergic neurons project to the spinal dorsal …

The search for new ligands to treat neuropathic pain remains a challenge. Recently,
oxytocin has emerged as an interesting molecule modulating nociception at central and …

The treatment of chronic pain arising from deep tissues is currently inadequate and there is
need for new pharmacological agents to provide analgesia. The endogenous paracrine …

Objectives: A review of the literature was conducted to assess the association between
oxytocin (OT) and pain. Methods: PsychInfo, PubMed, and Medline (EBSCO) research …

Oxytocin is a neuropeptide regulating social‐affiliative and reproductive behaviour in
mammals. Despite robust preclinical evidence for the antinociceptive effects and …

Pain is a ubiquitously unpleasant feeling among humans as well as many animal species
often caused by actual and potential tissue damage. However, it is absolutely crucial for our …

Background There is a need for novel analgesics with favorable risk to benefit profiles.
Oxytocin has recently gained attention for its potential analgesic properties. Aim The aim of …