Airway epithelial cells form a barrier to the outside world and are at the front line of mucosal
immunity. Epithelial apical junctional complexes are multiprotein subunits that promote cell …

Airway epithelium contributes significantly to the barrier function of airway tract. Mucociliary
escalator, intercellular apical junctional complexes which regulate paracellular permeability …

Although asthma is an inflammatory disorder of the conducting airways involving TH2-type T
cells, there is increasing evidence for an important role played by the epithelium in …

The bronchial epithelium is pivotally involved in the provision of chemical, physical, and
immunologic barriers to the inhaled environment. These barriers serve to maintain normal …

The bronchial epithelium is constantly exposed to a wide range of environmental materials
present in inhaled air, including noxious gases and anthropogenic and natural particulates …

The respiratory epithelium constitutes the physical barrier between the human body and the
environment, thus providing functional and immunological protection. It is often exposed to …

The integrity of the airway epithelium in patients with asthma is often disrupted, with loss of
epithelial cell–cell contacts. Airway epithelial barrier dysfunction may have important …

The respiratory epithelium provides a physical, functional, and immunologic barrier to
protect the host from the potential harming effects of inhaled environmental particles and to …

Epithelial barriers of the skin, gastrointestinal tract, and airway serve common critical
functions, such as maintaining a physical barrier against environmental insults and …

The bronchial epithelium is continuously exposed to a multitude of noxious challenges in
inhaled air. Cellular contact with most damaging agents is reduced by the action of the …