Cryptococcus neoformans has been designated as critical fungal pathogens by the World
Health Organization, mainly due to limited treatment options and the prevalence of …

Isobavachalcone (IBC) is a natural flavonoid with multiple pharmacological properties. This
study aimed to evaluate the efficacy of IBC against planktonic growth and biofilms of …

Cryptococcus neoformans is an important opportunistic fungal pathogen that causes various
infections. Here, the antifungal and antibiofilm activities of plumbagin against C. neoformans …

The recalcitrant biofilm formed by fungus Cryptococcus neoformans is a life-threatening
pathogenic condition responsible for further intensifying cryptococcosis. Considering the …

Cryptococcus neoformans is one of the most important human fungal pathogens; however,
no new therapies have been developed in over 50 years. Fungicidal activity is crucially …

Fungal populations are commonly found in natural environments and present enormous
health care challenges, due to increased resistance to antifungal agents. Paeonol exhibits …

Cinnamaldehyde has a broad range of biological activities, which include antibiofilm and
anthelmintic activities. The ever-growing problem of drug resistance and limited treatment …

Currently, the therapeutic effect on cryptococcal infection patients is hindered by toxicity and
drug resistance, making it urgent to discover alternative antifungals. Calcium channel …

Isobavachalcone (IBC) is a natural small molecule with various biological activities;
however, its inhibitory effects on Cryptococcus neoformans remain unclear. In our study, IBC …

Candida albicans is an opportunistic pathogenic yeast and is responsible for candidiasis. It
readily colonizes host tissues and implant devices, and forms biofilms, which play an …