Characteristics of large patient‐reported outcomes: where can one million seizures get us?
V Ferastraoaru, DM Goldenholz, S Chiang… - Epilepsia …, 2018 - Wiley Online Library
Objective To analyze data from Seizure Tracker, a large electronic seizure diary, including
comparison of seizure characteristics among different etiologies, temporal patterns in …
comparison of seizure characteristics among different etiologies, temporal patterns in …
Seizure diaries for clinical research and practice: limitations and future prospects
RS Fisher, DE Blum, B DiVentura, J Vannest… - Epilepsy & Behavior, 2012 - Elsevier
PURPOSE: An NINDS-sponsored conference in April of 2011 reviewed issues in epilepsy
clinical trials. One goal was to clarify new electronic methods for recording seizure …
clinical trials. One goal was to clarify new electronic methods for recording seizure …
Assessing seizure burden in pediatric epilepsy using an electronic medical record–based tool through a common data element approach
MP Fitzgerald, MC Kaufman, SL Massey… - …, 2021 - Wiley Online Library
Objective Improvement in epilepsy care requires standardized methods to assess disease
severity. We report the results of implementing common data elements (CDEs) to document …
severity. We report the results of implementing common data elements (CDEs) to document …
Is seizure frequency variance a predictable quantity?
DM Goldenholz, SR Goldenholz, R Moss… - Annals of clinical …, 2018 - Wiley Online Library
Background There is currently no formal method for predicting the range expected in an
individual's seizure counts. Having access to such a prediction would be of benefit for …
individual's seizure counts. Having access to such a prediction would be of benefit for …
[HTML][HTML] Counting seizures: The primary outcome measure in epileptology from the patients' perspective
Purpose Patient-reported seizure counts represent a key outcome measure for individual
treatments and clinical studies in epileptology. Video-EEG based research, however …
treatments and clinical studies in epileptology. Video-EEG based research, however …
Seizure cycles in focal epilepsy
Importance Focal epilepsy is characterized by the cyclical recurrence of seizures, but, to our
knowledge, the prevalence and patterns of seizure cycles are unknown. Objective To …
knowledge, the prevalence and patterns of seizure cycles are unknown. Objective To …
A big data approach to the development of mixed‐effects models for seizure count data
Objective Our objective was to develop a generalized linear mixed model for predicting
seizure count that is useful in the design and analysis of clinical trials. This model also may …
seizure count that is useful in the design and analysis of clinical trials. This model also may …
Use of an online epilepsy diary to characterize repetitive seizures
RS Fisher, E Bartfeld, JA Cramer - Epilepsy & Behavior, 2015 - Elsevier
Significance Little is known about patterns of seizures that occur multiple times a day,
sometimes called clusters or serial seizures. Objective The online diary, My Epilepsy Diary …
sometimes called clusters or serial seizures. Objective The online diary, My Epilepsy Diary …
Epilepsy as a dynamic disease: A Bayesian model for differentiating seizure risk from natural variability
Objective A fundamental challenge in treating epilepsy is that changes in observed seizure
frequencies do not necessarily reflect changes in underlying seizure risk. Rather, changes in …
frequencies do not necessarily reflect changes in underlying seizure risk. Rather, changes in …
Who seizes longest? Impact of clinical and demographic factors
E Kaufmann, M Seethaler, M Lauseker, M Fan… - …, 2020 - Wiley Online Library
Objective To investigate the impact of clinical and demographic parameters on the duration
of focal onset seizures with and without secondary generalization using precise duration …
of focal onset seizures with and without secondary generalization using precise duration …