Context Recurrent spontaneous abortion (RSA) is defined as the loss of 2 or more
consecutive intrauterine pregnancies with the same sexual partner in the first trimester …

Background Repeated implantation failure (RIF) leads to a waste of high-quality embryos
and remains a challenge in assisted reproductive technology. During early human …

Endometrial decidualization is critical to successful uterine receptivity and embryo
implantation. Dysfunction of decidualization is associated with some pregnancy-related …

BMP2 is a critical factor that is involved in the processes of embryo implantation and uterine
decidualization. The expression of cyclooxygenase (COX) and subsequent prostaglandin …

A critical role of progesterone (P) during early pregnancy is to induce differentiation of the
endometrial stromal cells into specialized decidual cells that support the development of the …

The process of implantation, necessary for all viviparous birth, consists of tightly regulated
events, including apposition of the blastocyst, attachment to the uterine lumen, and …

Defective expression of endometrial BMP-2 contributes to subfertility in women with
unexplained infertility Arzu Yurci1,*, Nur Dokuzeylul Gungor2, Tugba Gurbuz3 1Gynecology …

In women, the window of implantation is limited to a brief 2-to 3-day period characterized by
optimal levels of circulating ovarian hormones and a receptive endometrium. Although the …

Sertoli cells are essential for regulating normal spermatogenesis. However, the mechanisms
underlying human Sertoli cell development remain largely elusive. Here we examined the …

Embryo implantation and trophoblast invasion are principal limiting factors of pregnancy
establishment. Aberrant embryo development or improper trophoblast differentiation and …