Lipid accumulation and SNF1 transcriptional analysis of Mucor circinelloides on xylose under nitrogen limitation

Y Zhang, Y Yang, S Zhang, Q Liu, W Dang… - Antonie Van …, 2023 - Springer
Abstract Sucrose non-fermenting 1 (SNF1) plays a crucial role in utilizing non-glucose
carbon sources and regulating lipid metabolism. However, the mechanism by which SNF1 …

Effect of Different Carbons on Lipid Production and SNF1 Transcription in Mucor Circinelloides

Y Zhang, Y Yang, H Zhang, Q Liu, Y Song - Indian Journal of Microbiology, 2023 - Springer
Abstract Sucrose non-fermenting 1 (SNF1) protein kinase plays an important role in the
utilization of selective carbon sources and regulation of lipid metabolism. In order to further …

Lipid Accumulation by Snf-β Engineered Mucor circinelloides Strains on Glucose and Xylose

Y Zhang, Y Yang, Q Liu, S Li, Y Song - Applied Biochemistry and …, 2023 - Springer
Abstract Sucrose non-fermenting 1 (SNF1) protein kinase plays the regulatory roles in the
utilization of selective carbon sources and lipid metabolism. Previously, the role of β subunit …

Role of Snf-β in lipid accumulation in the high lipid‐producing fungus Mucor circinelloides WJ11

S Nosheen, T Naz, J Yang, SA Hussain… - Microbial Cell …, 2021 - Springer
Background Mucor circinelloides WJ11 is a high-lipid producing strain and an excellent
producer of γ-linolenic acid (GLA) which is crucial for human health. We have previously …

Proteomics analysis of high lipid-producing strain Mucor circinelloides WJ11: an explanation for the mechanism of lipid accumulation at the proteomic level

X Tang, X Zan, L Zhao, H Chen, YQ Chen, W Chen… - Microbial cell …, 2016 - Springer
Abstract Background The oleaginous fungus, Mucor circinelloides, is attracting considerable
interest as it produces oil rich in γ-linolenic acid. Nitrogen (N) deficiency is a common …

The role of areA in lipid accumulation in high lipid-producing fungus Mucor circinelloides WJ11

H Hu, P Li, S Li, X Wang, H Mohamed… - … et Biophysica Acta (BBA …, 2024 - Elsevier
In the oleaginous fungus Mucor circinelloides, lipid accumulation is regulated by nitrogen
metabolism, which is regulated by the areA gene, a member of the GATA zinc finger …

The role of a xylose isomerase pathway in the conversion of xylose to lipid in Mucor circinelloides

L Chu, X Zan, X Tang, L Zhao, H Chen, YQ Chen… - RSC …, 2016 - pubs.rsc.org
The xylose isomerase (XI) pathway, which converts xylose in lignocellulosic materials into
intermediate metabolites, does not commonly exist in filamentous fungi. The genomic …

Comparison of Biochemical Activities between High and Low Lipid-Producing Strains of Mucor circinelloides: An Explanation for the High Oleaginicity of Strain WJ11

X Tang, H Chen, YQ Chen, W Chen, V Garre, Y Song… - PloS one, 2015 - journals.plos.org
The oleaginous fungus, Mucor circinelloides, is one of few fungi that produce high amounts
of γ-linolenic acid (GLA); however, it usually only produces< 25% lipid. Nevertheless, a new …

Improved glucose and xylose co-utilization by overexpression of xylose isomerase and/or xylulokinase genes in oleaginous fungus Mucor circinelloides

X Zan, J Sun, L Chu, F Cui, S Huo, Y Song… - Applied Microbiology …, 2021 - Springer
Most of the oleaginous microorganisms cannot assimilate xylose in the presence of glucose,
which is the major bottleneck in the bioconversion of lignocellulose to biodiesel. Our present …

Simultaneous overexpression of ∆6-, ∆12- and ∆9-desaturases enhanced the production of γ-linolenic acid in Mucor circinelloides WJ11

X Wang, J Yang, H Mohamed, AM Shah, S Li… - Frontiers in …, 2022 - frontiersin.org
Mucor circinelloides WJ11, an oleaginous filamentous fungus, produces 36% lipid of its cell
dry weight when cultured in a high C/N ratio medium, however, the yield of γ-linolenic acid …