Molecular Mechanisms of Flavonoids against Tumor Gamma-Herpesviruses and Their Correlated Cancers—A Focus on EBV and KSHV Life Cycles and …

STS Hassan, M Šudomová - International Journal of Molecular Sciences, 2022 - mdpi.com
Epstein–Barr virus (EBV) and Kaposi sarcoma-associated herpesvirus (KSHV) are cancer-
causing viruses that belong to human gamma-herpesviruses. They are DNA viruses known …

Insights into antiviral properties and molecular mechanisms of non-flavonoid polyphenols against human herpesviruses

STS Hassan, M Šudomová, A Mazurakova… - International Journal of …, 2022 - mdpi.com
Herpesviruses are one of the most contagious DNA viruses that threaten human health,
causing severe diseases, including, but not limited to, certain types of cancer and …

Flavonoids target human herpesviruses that infect the nervous system: Mechanisms of action and therapeutic insights

M Šudomová, K Berchová-Bímová, A Mazurakova… - Viruses, 2022 - mdpi.com
Human herpesviruses (HHVs) are large DNA viruses with highly infectious characteristics.
HHVs can induce lytic and latent infections in their host, and most of these viruses are …

Flavonoids with anti-herpes simplex virus properties: deciphering their mechanisms in disrupting the viral life cycle

M Šudomová, STS Hassan - Viruses, 2023 - mdpi.com
The herpes simplex virus (HSV) is a double-stranded DNA human virus that causes
persistent infections with recurrent outbreaks. HSV exists in two forms: HSV-1, responsible …

Natural products and their derivatives against human herpesvirus infection

C Ruchawapol, M Yuan, SM Wang, WW Fu, HX Xu - Molecules, 2021 - mdpi.com
Herpesviruses establish long-term latent infection for the life of the host and are known to
cause numerous diseases. The prevalence of viral infection is significantly increased and …

The role of gammaherpesviruses in cancer pathogenesis

HC Jha, S Banerjee, ES Robertson - Pathogens, 2016 - mdpi.com
Worldwide, one fifth of cancers in the population are associated with viral infections. Among
them, gammaherpesvirus, specifically HHV4 (EBV) and HHV8 (KSHV), are two oncogenic …

Hampering Herpesviruses HHV-1 and HHV-2 Infection by Extract of Ginkgo biloba (EGb) and Its Phytochemical Constituents

M Sochocka, M Sobczyński, M Ochnik… - Frontiers in …, 2019 - frontiersin.org
Despite the availability of several anti-herpesviral agents, it should be emphasized that the
need for new inhibitors is highly encouraged due to the increasing resistant viral strains as …

Modulation of angiogenic processes by the human gammaherpesviruses, epstein–barr virus and kaposi's sarcoma-associated herpesvirus

R Rivera-Soto, B Damania - Frontiers in microbiology, 2019 - frontiersin.org
Angiogenesis is the biological process by which new blood vessels are formed from pre-
existing vessels. It is considered one of the classic hallmarks of cancer, as pathological …

Targeting host cellular factors as a strategy of therapeutic intervention for herpesvirus infections

K Asha, N Sharma-Walia - Frontiers in Cellular and Infection …, 2021 - frontiersin.org
Herpesviruses utilize various host factors to establish latent infection, survival, and spread
disease in the host. These factors include host cellular machinery, host proteins, gene …

Berberine in human oncogenic herpesvirus infections and their linked cancers

M Šudomová, K Berchová-Bímová, S Marzocco… - Viruses, 2021 - mdpi.com
Human herpesviruses are known to induce a broad spectrum of diseases, ranging from
common cold sores to cancer, and infections with some types of these viruses, known as …