[HTML][HTML] Hypothesizing in the face of the opioid crisis coupling Genetic Addiction Risk Severity (GARS) testing with electrotherapeutic nonopioid modalities such as H …
A Gupta, A Bowirrat, LL Gomez, D Baron… - International Journal of …, 2022 - mdpi.com
In the United States, amid the opioid overdose epidemic, nonaddicting/nonpharmacological
proven strategies are available to treat pain and manage chronic pain effectively without …
proven strategies are available to treat pain and manage chronic pain effectively without …
[HTML][HTML] Coupling genetic addiction risk score (GARS) with electrotherapy: fighting iatrogenic opioid dependence
K Blum, M Oscar-Berman, N DiNubile… - Journal of addiction …, 2013 - ncbi.nlm.nih.gov
The endemic of legal opioid iatrogenic induced prescription drug abuse is of major world-
wide concern. Understanding pain pathways and the role of dopaminergic tone in the …
wide concern. Understanding pain pathways and the role of dopaminergic tone in the …
[HTML][HTML] High genetic addiction risk score (GARS) in chronically prescribed severe chronic opioid probands attending multi-pain clinics: an open clinical pilot trial
M Moran, K Blum, JV Ponce, L Lott… - Molecular …, 2021 - Springer
Millions of Americans experience pain daily. In 2017, opioid overdose claimed 64,000 lives
increasing to 84,000 lives in 2020, resulting in a decrease in national life expectancy …
increasing to 84,000 lives in 2020, resulting in a decrease in national life expectancy …
[HTML][HTML] Epigenetic alterations in prescription opioid misuse: new strategies for precision pain management
MC Gerra, C Dallabona, L Arendt-Nielsen - Genes, 2021 - mdpi.com
Prescription opioids are used for some chronic pain conditions. However, generally, long-
term therapy has unwanted side effects which may trigger addiction, overdose, and …
term therapy has unwanted side effects which may trigger addiction, overdose, and …
Neuropharmacological and neurogenetic correlates of opioid use disorder (OUD) as a function of ethnicity: relevance to precision addiction medicine
T Abijo, K Blum… - Current …, 2020 - ingentaconnect.com
Background: Over 100 people die daily from opioid overdose and $78.5 B per year is spent
on treatment efforts, however, the real societal cost is multifold greater. Alternative strategies …
on treatment efforts, however, the real societal cost is multifold greater. Alternative strategies …
[HTML][HTML] Insurance companies fighting the peer review empire without any validity: the case for addiction and pain modalities in the face of an American drug epidemic
K Blum, W Jacobs, EJ Modestino, N DiNubile… - SEJ surgery and …, 2018 - ncbi.nlm.nih.gov
Abstract The United States are amid an opioid overdose epidemic; we are challenged to
provide non-addicting/non-pharmacological alternatives to assist in pain attenuation. There …
provide non-addicting/non-pharmacological alternatives to assist in pain attenuation. There …
The science of addiction through the lens of opioid treatment for chronic noncancer pain
W Umberger, L Gaddis - Pain Management Nursing, 2020 - Elsevier
Addiction is a chronic, relapsing brain disease. It is not the same as physical dependence
(ie, withdrawal) and tolerance, but is characterized by loss of control over the use of the …
(ie, withdrawal) and tolerance, but is characterized by loss of control over the use of the …
A potential paradigm shift in opioid crisis management: The role of pharmacogenomics
D Eapen-John, AG Mohiuddin… - The World Journal of …, 2022 - Taylor & Francis
Pharmacogenetic investigations into the opioid crisis suggest genetic variation could be a
significant cause of opioid-related morbidity and mortality. Variability in opioid system genes …
significant cause of opioid-related morbidity and mortality. Variability in opioid system genes …
Unveiling the link between chronic pain and misuse of opioids and cannabis
Over 50 million Americans endure chronic pain where many do not receive adequate
treatment and self-medicate to manage their pain by taking substances like opioids and …
treatment and self-medicate to manage their pain by taking substances like opioids and …
[HTML][HTML] Global opioid epidemic: doomed to fail without genetically based precision addiction medicine (PAM™): lessons learned from America
K Blum, EJ Modestino, MC Gondré-Lewis… - Precision …, 2017 - ncbi.nlm.nih.gov
It is a reality that globally opioid deaths have soared for men and women of all social,
economic status and age from heroin and fentanyl overdoses. Specifically, in the United …
economic status and age from heroin and fentanyl overdoses. Specifically, in the United …