Activation and adoptive transfer of Epstein–Barr virus-specific cytotoxic T cells in solid organ transplant patients with posttransplant lymphoproliferative disease

R Khanna, S Bell, M Sherritt… - Proceedings of the …, 1999 - National Acad Sciences
The treatment of Epstein–Barr virus (EBV)-associated lymphoproliferative disease (PTLD) in
EBV seronegative solid organ transplant recipients who acquire their EBV infection after …

Infusion of autologous Epstein-Barr virus (EBV)–specific cytotoxic T cells for prevention of EBV-related lymphoproliferative disorder in solid organ transplant recipients …

P Comoli, M Labirio, S Basso, F Baldanti… - Blood, The Journal …, 2002 - ashpublications.org
Epstein-Barr virus (EBV)–associated posttransplantation lymphoproliferative disorders
(PTLDs) are a well-recognized complication of immunosuppression in solid organ transplant …

Reconstitution of the latent T-lymphocyte response to Epstein-Barr virus is coincident with long-term recovery from posttransplant lymphoma after adoptive …

MA Sherritt, M Bharadwaj, JM Burrows… - …, 2003 - journals.lww.com
Background. Adoptive transfer of Epstein-Barr virus (EBV)-specific cytotoxic T lymphocytes
(CTLs) has been used to treat EBV-induced posttransplant lymphoproliferative disease …

Treatment of solid organ transplant recipients with autologous Epstein Barr virus–specific cytotoxic T lymphocytes (CTLs)

B Savoldo, JA Goss, MM Hammer, L Zhang, T Lopez… - Blood, 2006 - ashpublications.org
We have investigated the in vivo safety, efficacy, and persistence of autologous Epstein Barr
virus (EBV)–specific cytotoxic T lymphocytes (CTLs) for the treatment of solid organ …

Establishment and characterization of a bank of cytotoxic T lymphocytes for immunotherapy of epstein-barr virus-associated diseases

GM Wilkie, C Taylor, MM Jones, DM Burns… - Journal of …, 2004 - journals.lww.com
Abstract Adoptive immunotherapy using Epstein-Barr virus (EBV)-specific cytotoxic T
lymphocytes (CTL) generated ex vivo can be an effective treatment of EBV-positive …

Effective and long-term control of EBV PTLD after transfer of peptide-selected T cells

A Moosmann, I Bigalke, J Tischer… - Blood, The Journal …, 2010 - ashpublications.org
Posttransplantation lymphoproliferative disease (PTLD) associated with Epstein-Barr virus
(EBV) is a life-threatening complication after allogeneic hematopoietic stem cell …

COMPLETE REGRESSION OF POSTTRANSPLANT LYMPHOPROLIFERATIVE DISEASE USING PARTIALLY HLA-MATCHED EPSTEIN BARR VIRUS-SPECIFIC …

T Haque, C Taylor, GM Wilkie, P Murad, PL Amlot… - …, 2001 - journals.lww.com
Background. Adoptive immunotherapy with autologous and donor-derived cytotoxic T
lymphocytes (CTL) has recently been used to treat Epstein Barr virus (EBV)-positive …

The development of cellular immunity to Epstein-Barr virus after allogeneic bone marrow transplantation

KG Lucas, TN Small, G Heller, B Dupont, RJ O'Reilly - 1996 - ashpublications.org
Epstein-Barr virus-induced lymphoproliferative disease (EBV-LPD) is a potentially lethal
complication during the first 6 months after allogeneic bone marrow transplantation (BMT) …

GENERATION OF AUTOLOGOUS EPSTEIN-BARR VIRUS–SPECIFIC CYTOTOXIC T CELLS FOR ADOPTIVE IMMUNOTHERAPY IN SOLID ORGAN TRANSPLANT …

B Savoldo, J Goss, Z Liu, MH Huls, S Doster… - …, 2001 - journals.lww.com
Background. Epstein-Barr virus (EBV)-driven posttransplant lymphoproliferative disorders
(PTLD) affect 2%–27% of solid organ transplant (SOT) recipients. Adoptive immunotherapy …

Epstein-Barr virus (EBV)-specific cytotoxic T lymphocytes for the prevention and treatment of EBV-associated post-transplant lymphomas

Z Liu, B Savoldo, H Huls, T Lopez, A Gee… - … Disorders in Congenital …, 2002 - Springer
Abstract The Epstein-Barr virus (EBV)-associated lymphoproliferative disorders (LPD) that
occur in individuals immunosuppressed by solid organ transplant (SOT) or T cell-depleted …