Theranostic radiopharmaceuticals: established agents in current use

JR Ballinger - The British journal of radiology, 2018 - academic.oup.com
Although use of the term “theranostic” is relatively recent, the concept goes back to the
earliest days of nuclear medicine, with the use of radioiodine for diagnosis and therapy of …

Theranostic concepts: more than just a fashion trend—introduction and overview

K Herrmann, SM Larson, WA Weber - Journal of Nuclear Medicine, 2017 - Soc Nuclear Med
The term theranostics is today perceived as the combination of a predictive biomarker with a
therapeutic agent. Use of this term began at the end of the last century and has steadily …

Radiopharmaceuticals: state of the art

AM Verbruggen - European journal of nuclear medicine, 1990 - Springer
In the past four years most of the effort in radiopharmaceutical chemistry has been devoted
to compounds for positron emission tomography, but widespread use of this technique is still …

Future of theranostics: an outlook on precision oncology in nuclear medicine

T Langbein, WA Weber, M Eiber - Journal of Nuclear Medicine, 2019 - Soc Nuclear Med
Molecular alterations in malignant disease result in the expression or upregulations of
various targets that can be used for imaging and treatment with radiopharmaceuticals. This …

Clinical perspectives of theranostics

S Okamoto, T Shiga, N Tamaki - Molecules, 2021 - mdpi.com
Theranostics is a precision medicine which integrates diagnostic nuclear medicine and
radionuclide therapy for various cancers throughout body using suitable tracers and …

Targeted radionuclide therapy: a historical and personal review

SJ Goldsmith - Seminars in Nuclear Medicine, 2020 - Elsevier
This review traces the development of targeted radionuclide therapy (TRT)(the Magic Bullet)
from the discovery of radioactivity in nature and the subsequent discovery of artificial …

From bench to bedside—the bad Berka experience with first-in-human studies

J Zhang, A Singh, HR Kulkarni, C Schuchardt… - Seminars in nuclear …, 2019 - Elsevier
Precision oncology is being driven by rapid advances in novel diagnostics and therapeutic
interventions, with treatments targeted to the needs of individual patients on the basis of …

Development of radiotracers for oncology–the interface with pharmacology

R Sharma, E Aboagye - British journal of pharmacology, 2011 - Wiley Online Library
There is an increasing role for positron emission tomography (PET) in oncology, particularly
as a component of early phase clinical trials. As a non‐invasive functional imaging modality …

Recent advances in theranostics and challenges for the future

JH Turner - The British journal of radiology, 2018 - academic.oup.com
Theranostic nuclear oncology is on the cusp of adoption into routine clinical management of
neuroendocrine tumours (NETs) following publication of the Phase 3 randomised controlled …

Theranostic approaches in nuclear medicine: current status and future prospects

L Filippi, A Chiaravalloti, O Schillaci… - Expert review of …, 2020 - Taylor & Francis
Introduction: Theranostics is an emerging field in which diagnosis and specific targeted
therapy are combined to achieve a personalized treatment approach to the patient. In …