[HTML][HTML] Alzheimer's disease as a major public health concern: Role of dietary saponins in mitigating neurodegenerative disorders and their underlying mechanisms

AA Abduljawad, MA Elawad, MEM Elkhalifa, A Ahmed… - Molecules, 2022 - mdpi.com
Saponins are triterpenoid or steroidal glycosides and are an important group of naturally
occurring compounds of plant origin. They exhibit diverse pharmacological potentials …

Neuroprotection by saponins

A Sun, X Xu, J Lin, X Cui, R Xu - Phytotherapy research, 2015 - Wiley Online Library
Saponins, an important group of bioactive plant natural products, are glycosides of
triterpenoid or steroidal aglycones. Their diverse biological activities are ascribed to their …

[HTML][HTML] Saponins: A concise review on food related aspects, applications and health implications

K Sharma, R Kaur, S Kumar, RK Saini, S Sharma… - Food Chemistry …, 2023 - Elsevier
In recent years, saponins are gaining extensive attention due to their occurrence in several
plants. Saponins and their derivatives are versatile glycosidic compounds, which play an …

Positive health benefits of saponins from edible legumes: Phytochemistry and pharmacology

O Kareem, T Ali, LA Dar, SA Mir, R Rashid… - Edible Plants in Health …, 2022 - Springer
Saponins are the naturally occurring phytochemicals present in most vegetables, edible
legumes, and herbs. These constitute a chemically diverse group of compounds that contain …

Saponin: properties, methods of evaluation and applications

E Moghimipour, S Handali - Annual Research & Review in …, 2014 - journal.send2sub.com
Saponins are secondary metabolites with high molecular weight. They present in a wide
range of plant species and are distributed throughout the bark, leaves, stems, roots and …

Saponins: the phytochemical with an emerging potential for curing clinical depression

G Abbas, K Rauf, W Mahmood - Natural product research, 2015 - Taylor & Francis
Depression is on the rise globally and expected to lead in global burden of diseases by
2030. The current therapy has serious limitations in terms of safety, efficacy, tolerability and …

[HTML][HTML] Perspectives on saponins: food functionality and applications

YP Timilsena, A Phosanam, R Stockmann - International Journal of …, 2023 - mdpi.com
Saponins are a diverse group of naturally occurring plant secondary metabolites present in
a wide range of foods ranging from grains, pulses, and green leaves to sea creatures. They …

The bioactivity of saponins: triterpenoid and steroidal glycosides

DM Gurfinkel - Drug metabolism and drug interactions, 2000 - degruyter.com
Triterpenoid and steroidal glycosides, referred to collectively as saponins, are bioactive
compounds present naturally in many plants. They have considerable potential as …

[HTML][HTML] Crude Saponin from Platycodon grandiflorum Attenuates Aβ-Induced Neurotoxicity via Antioxidant, Anti-Inflammatory and Anti-Apoptotic Signaling Pathways

YJ Ji, S Kim, JJ Kim, GY Jang, M Moon, HD Kim - Antioxidants, 2021 - mdpi.com
Although Platycodon grandiflorum saponins exhibit many beneficial biological effects in
various diseases and conditions, how they protect nerve cells against neurodegenerative …

Saponins: Anti-diabetic principles from medicinal plants–A review

OO Elekofehinti - Pathophysiology, 2015 - Elsevier
Diabetes mellitus (DM) represents a global health problem. It is the most common of the
endocrine disorders and is characterized by chronic hyperglycemia due to relative or …