Multiple therapeutic approaches of glioblastoma multiforme: from terminal to therapy

S Kumari, R Gupta, RK Ambasta, P Kumar - Biochimica et Biophysica Acta …, 2023 - Elsevier
Glioblastoma multiforme (GBM) is an aggressive brain cancer showing poor prognosis.
Currently, treatment methods of GBM are limited with adverse outcomes and low survival …

Recent advances in the therapeutic strategies of glioblastoma multiforme

AF Aldoghachi, AF Aldoghachi, K Breyne, KH Ling… - Neuroscience, 2022 - Elsevier
Glioblastoma multiforme (GBM) is one of the most common, most formidable, and deadliest
malignant types of primary astrocytoma with a poor prognosis. At present, the standard of …

On glioblastoma and the search for a cure: where do we stand?

J Bianco, C Bastiancich, A Jankovski… - Cellular and Molecular …, 2017 - Springer
Although brain tumours have been documented and recorded since the nineteenth century,
2016 marked 90 years since Percival Bailey and Harvey Cushing coined the term …

Glioblastoma microenvironment and invasiveness: new insights and therapeutic targets

JI Erices, C Bizama, I Niechi, D Uribe… - International Journal of …, 2023 - mdpi.com
Glioblastoma (GBM) is the most common and malignant primary brain cancer in adults.
Without treatment the mean patient survival is approximately 6 months, which can be …

[HTML][HTML] Glioblastoma: new therapeutic strategies to address cellular and genomic complexity

X Cai, ME Sughrue - Oncotarget, 2018 - ncbi.nlm.nih.gov
Glioblastoma (GBM) is the most invasive and devastating primary brain tumor with a median
overall survival rate about 18 months with aggressive multimodality therapy. Its unique …

Current opportunities for targeting dysregulated neurodevelopmental signaling pathways in glioblastoma

D Drakulic, M Schwirtlich, I Petrovic, M Mojsin… - Cells, 2022 - mdpi.com
Glioblastoma (GBM) is the most common and highly lethal type of brain tumor, with poor
survival despite advances in understanding its complexity. After current standard therapeutic …

Current perspectives on therapies, including drug delivery systems, for managing glioblastoma multiforme

M Bhaskaran, VG Devegowda, VK Gupta… - ACS chemical …, 2020 - ACS Publications
Glioblastoma multiforme (GBM), a standout among the most dangerous class of central
nervous system (CNS) cancer, is most common and is an aggressive malignant brain tumor …

Glioblastoma multiforme: novel therapeutic targets

M Muir, S Gopakumar, J Traylor, S Lee… - Expert Opinion on …, 2020 - Taylor & Francis
Introduction The increasingly detailed genetic characterization of glioblastoma (GBM) has
failed to translate into meaningful breakthroughs in treatment. This is likely to be attributed to …

Molecular targeted therapy: A new avenue in glioblastoma treatment

O El Atat, R Naser, M Abdelkhalek… - Oncology …, 2023 - spandidos-publications.com
Glioblastoma, also referred to as glioblastoma multiforme (GBM), is grade IV astrocytoma
characterized by being fast‑growing and the most aggressive brain tumor. In adults, it is the …

[HTML][HTML] Glioblastoma multiforme: an overview of emerging therapeutic targets

OG Taylor, JS Brzozowski, KA Skelding - Frontiers in oncology, 2019 - frontiersin.org
Glioblastoma multiforme (GBM) is the most common and aggressive malignant primary brain
tumour in humans and has a very poor prognosis. The existing treatments have had limited …