Protein subcellular localization is tightly controlled and intimately linked to protein function in
health and disease. Capturing the spatial proteome—that is, the localizations of proteins and …

The eukaryotic cell is compartmentalized into subcellular niches, including membrane-
bound and membrane-less organelles. Proteins localize to these niches to fulfil their …

Spatial proteomics is an interdisciplinary field that investigates the localization and dynamics
of proteins, and it has gained extensive attention in recent years, especially the subcellular …

Subcellular localization is a main determinant of protein function; however, a global view of
cellular proteome organization remains relatively unexplored. We have developed a robust …

Subcellular localization critically influences protein function, and cells control protein
localization to regulate biological processes. We have developed and applied Dynamic …

Motivation: Experimental spatial proteomics, ie the high-throughput assignment of proteins
to sub-cellular compartments based on quantitative proteomics data, promises to shed new …

Information on protein localization on the subcellular level is important to map and
characterize the proteome and to better understand cellular functions of proteins. Here we …

For a complete understanding of a system's processes and each protein's role in health and
disease, it is essential to study protein expression with a spatial resolution, as the exact …

Spatial transcriptomics and proteomics provide complementary information that
independently transformed our understanding of complex biological processes. However …

Characterizing the proteome composition of organelles and subcellular regions of living
cells can facilitate the understanding of cellular organization as well as protein interactome …