Tracers and imaging of fatty acid and energy metabolism of human adipose tissues

AC Carpentier - Physiology, 2024 - journals.physiology.org
White adipose tissue and brown adipose tissue (WAT and BAT) regulate fatty acid
metabolism and control lipid fluxes to other organs. Dysfunction of these key metabolic …

Imaging of adipose tissue

R Berry, CD Church, MT Gericke, E Jeffery… - Methods in …, 2014 - Elsevier
Adipose tissue is an endocrine organ that specializes in lipid metabolism and is distributed
throughout the body in distinct white adipose tissue (WAT) and brown adipose tissue (BAT) …

Imaging metabolically active fat: a literature review and mechanistic insights

J Frankl, A Sherwood, DJ Clegg, PE Scherer… - International journal of …, 2019 - mdpi.com
Currently, obesity is one of the leading causes death in the world. Shortly before 2000,
researchers began describing metabolically active adipose tissue on cancer-surveillance …

Proton MR spectroscopy measurements of white and brown adipose tissue in healthy humans: relaxation parameters and unsaturated fatty acids

R Ouwerkerk, A Hamimi, J Matta, KZ Abd-Elmoniem… - Radiology, 2021 - pubs.rsna.org
Background Activation of brown adipose tissue (BAT) in rodents increases lipolysis in white
adipose tissue (WAT) and improves glucose tolerance. Adult humans can have …

Substrate utilization by brown adipose tissue: what's hot and what's not?

BT McNeill, NM Morton, RH Stimson - Frontiers in endocrinology, 2020 - frontiersin.org
Our understanding of brown adipose tissue (BAT) function in humans has increased rapidly
over the past 10 years. This is predominantly due to the development of powerful non …

Brown adipose tissue energy metabolism in humans

AC Carpentier, DP Blondin, KA Virtanen… - Frontiers in …, 2018 - frontiersin.org
The demonstration of metabolically active brown adipose tissue (BAT) in humans primarily
using positron emission tomography coupled to computed tomography (PET/CT) with the …

Functional characterization of human brown adipose tissue metabolism

MA Richard, H Pallubinsky, DP Blondin - Biochemical Journal, 2020 - portlandpress.com
Brown adipose tissue (BAT) has long been described according to its histological features
as a multilocular, lipid-containing tissue, light brown in color, that is also responsive to the …

Human brown fat radiodensity indicates underlying tissue composition and systemic metabolic health

M u Din, J Raiko, T Saari, V Saunavaara… - The Journal of …, 2017 - academic.oup.com
Context: Metabolic imaging studying brown adipose tissue (BAT) physiology has increased,
in which computed tomography (CT) is commonly used as an anatomical reference for …

Brown adipose tissue in humans: detection and functional analysis using PET (positron emission tomography), MRI (magnetic resonance imaging), and DECT (dual …

M Borga, KA Virtanen, T Romu, OD Leinhard… - Methods in …, 2014 - Elsevier
If the beneficial effects of brown adipose tissue (BAT) on whole body metabolism, as
observed in nonhuman experimental models, are to be translated to humans, tools that …

Perspectives on brown adipose tissue imaging: insights from preclinical and clinical observations from the last and current century

JP Crandall, RL Wahl - Journal of Nuclear Medicine, 2021 - Soc Nuclear Med
Brown adipose tissue (BAT) was first described in the 16th century, but until late last century
had mainly been considered a tissue with the function of nonshivering thermogenesis …