Leptomeningeal disease (LMD) represents a devastating complication of advanced breast
cancer (ABC), with survival of< 5 months with multimodal treatment. The role of endocrine …

Leptomeningeal carcinomatosis carries a poor prognosis in breast cancer. Treatment
modalities are geared towards tumour molecular characteristics, as well as symptoms and …

Leptomeningeal carcinomatosis (LC) is a rare but challenging manifestation of advanced
breast cancer with a severe impact on morbidity and mortality. We performed a systematic …

The incidence of leptomeningeal carcinomatosis in breast cancer patients (LC-BC) is
increasing. Despite significantly affecting patient quality of life (QoL) and overall survival …

Leptomeningeal carcinomatosis (LC) is a metastatic complication of breast cancer that
imparts a very poor prognosis and distressing neurologic symptoms in affected patients …

Leptomeningeal carcinomatosis (LC) is an unmet medical need associated with death in 4–
6 weeks without treatment, delayed by 4 months in some patients with favorable prognosis …

Simple Summary Leptomeningeal carcinomatosis (LC) is a rare event in breast cancer (BC)
patients that carries an abysmal prognosis. Little progress has been made in this field in the …

Purpose Leptomeningeal disease (LMD) is an advanced metastatic disease presentation
portending a poor prognosis with minimal treatment options. The advent and widespread …

Clinical data supporting the best therapeutic approach in leptomeningeal disease (LMD;
also known as leptomeningeal metastases or leptomeningeal carcinomatosis) are lacking …

Leptomeningeal carcinomatosis is a devastating disease. Despite its numerous
complications, intrathecal (IT) chemotherapy remains a longstanding treatment for …