[HTML][HTML] A genome-wide association scan implicates DCHS2, RUNX2, GLI3, PAX1 and EDAR in human facial variation
K Adhikari, M Fuentes-Guajardo… - Nature …, 2016 - nature.com
We report a genome-wide association scan for facial features in∼ 6,000 Latin Americans.
We evaluated 14 traits on an ordinal scale and found significant association (P values< 5× …
We evaluated 14 traits on an ordinal scale and found significant association (P values< 5× …
[HTML][HTML] Identification of five novel genetic loci related to facial morphology by genome-wide association studies
Background Face morphology is strongly determined by genetic factors. However, only a
small number of genes related to face morphology have been identified to date. Here, we …
small number of genes related to face morphology have been identified to date. Here, we …
[HTML][HTML] Genome-wide association study reveals multiple loci influencing normal human facial morphology
JR Shaffer, E Orlova, MK Lee, EJ Leslie… - PLoS …, 2016 - journals.plos.org
Numerous lines of evidence point to a genetic basis for facial morphology in humans, yet
little is known about how specific genetic variants relate to the phenotypic expression of …
little is known about how specific genetic variants relate to the phenotypic expression of …
Genetic variants underlying differences in facial morphology in East Asian and European populations
Facial morphology—a conspicuous feature of human appearance—is highly heritable.
Previous studies on the genetic basis of facial morphology were performed mainly in …
Previous studies on the genetic basis of facial morphology were performed mainly in …
[HTML][HTML] A genome-wide association study identifies five loci influencing facial morphology in Europeans
Inter-individual variation in facial shape is one of the most noticeable phenotypes in
humans, and it is clearly under genetic regulation; however, almost nothing is known about …
humans, and it is clearly under genetic regulation; however, almost nothing is known about …
[HTML][HTML] Genome-wide association study of three-dimensional facial morphology identifies a variant in PAX3 associated with nasion position
Craniofacial morphology is highly heritable, but little is known about which genetic variants
influence normal facial variation in the general population. We aimed to identify genetic …
influence normal facial variation in the general population. We aimed to identify genetic …
[HTML][HTML] Genome-wide association study of facial morphology reveals novel associations with FREM1 and PARK2
Several studies have now shown evidence of association between common genetic variants
and quantitative facial traits in humans. The reported associations generally involve simple …
and quantitative facial traits in humans. The reported associations generally involve simple …
A GWAS in Latin Americans identifies novel face shape loci, implicating VPS13B and a Denisovan introgressed region in facial variation
To characterize the genetic basis of facial features in Latin Americans, we performed a
genome-wide association study (GWAS) of more than 6000 individuals using 59 landmark …
genome-wide association study (GWAS) of more than 6000 individuals using 59 landmark …
[HTML][HTML] Genomewide Association Study of African Children Identifies Association of SCHIP1 and PDE8A with Facial Size and Shape
JB Cole, M Manyama, E Kimwaga, J Mathayo… - PLoS …, 2016 - journals.plos.org
The human face is a complex assemblage of highly variable yet clearly heritable anatomic
structures that together make each of us unique, distinguishable, and recognizable …
structures that together make each of us unique, distinguishable, and recognizable …
Genome-wide mapping of global-to-local genetic effects on human facial shape
Genome-wide association scans of complex multipartite traits like the human face typically
use preselected phenotypic measures. Here we report a data-driven approach to …
use preselected phenotypic measures. Here we report a data-driven approach to …