SERS and Fluorescence-Active Multimodal Tessellated Scaffolds for Three-Dimensional Bioimaging

E Lenzi, D Jimenez de Aberasturi… - … Applied Materials & …, 2022 - ACS Publications
With the ever-increasing use of 3D cell models toward studying bio-nano interactions and
offering alternatives to traditional 2D in vitro and in vivo experiments, methods to image …

Using SERS tags to image the three‐dimensional structure of complex cell models

D Jimenez de Aberasturi… - Advanced Functional …, 2020 - Wiley Online Library
Methods to image complex 3D cell cultures are limited by issues such as fluorophore
photobleaching and decomposition, poor excitation light penetration, and lack of …

3D‐printed biocompatible scaffolds with built‐in nanoplasmonic sensors

C García‐Astrain, E Lenzi… - Advanced Functional …, 2020 - Wiley Online Library
Abstract 3D printing strategies have acquired great relevance toward the design of 3D
scaffolds with precise macroporous structures, for supported mammalian cell growth …

SERS-Active Printable Hydrogel for 3D Cell Culture and Imaging

W Wang, PJ Vikesland - Analytical Chemistry, 2023 - ACS Publications
Hydrogel-based three-dimensional (3D) cell culture systems mimic the salient elements of
extracellular matrices and promote native cell function. However, high-resolution 3D cell …

Non-invasive three-dimensional cell analysis in bioinks by Raman imaging

J Marzi, E Fuhrmann, E Brauchle, V Singer… - … Applied Materials & …, 2022 - ACS Publications
3D bioprinting is an emerging biofabrication strategy using bioinks, comprising cells and
biocompatible materials, to produce functional tissue models. Despite progress in building …

Nanocomposite scaffolds for monitoring of drug diffusion in three-dimensional cell environments by surface-enhanced Raman spectroscopy

J Plou, B Molina-Martínez, C García-Astrain… - Nano Letters, 2021 - ACS Publications
Monitoring dynamic processes in complex cellular environments requires the integration of
uniformly distributed detectors within such three-dimensional (3D) networks, to an extent that …

Robust encapsulation of biocompatible gold nanosphere assemblies for bioimaging via surface enhanced Raman scattering

M Schumacher… - Advanced Optical …, 2022 - Wiley Online Library
Controlled assembly of gold nanoparticles (AuNPs) into clusters is a promising avenue for
the development of sensitive bioimaging and diagnostic tools based on surface‐enhanced …

Live-cell surface-enhanced Raman spectroscopy imaging of intracellular pH: From two dimensions to three dimensions

Y Zhang, D Jimenez de Aberasturi… - ACS …, 2020 - ACS Publications
Visualization of intracellular pH (i-pH) using surface-enhanced Raman spectroscopy (SERS)
plays an important role toward understanding of cellular processes including their …

Surface-enhanced Raman scattering tags for three-dimensional bioimaging and biomarker detection

E Lenzi, D Jimenez de Aberasturi, LM Liz-Marzán - ACS sensors, 2019 - ACS Publications
We have recently witnessed a major improvement in the quality of nanoparticles encoded
with Raman-active molecules (SERS tags). Such progress relied mainly on a major …

[HTML][HTML] 3D optical imaging of multiple SERS nanotags in cells

S McAughtrie, K Lau, K Faulds, D Graham - Chemical Science, 2013 - pubs.rsc.org
Recent studies have clearly demonstrated that Raman and surface enhanced Raman
scattering (SERS) spectroscopies are information rich, non-destructive techniques for the …