Early detection of diabetic peripheral neuropathy: a focus on small nerve fibres

J Burgess, B Frank, A Marshall, RS Khalil, G Ponirakis… - Diagnostics, 2021 - mdpi.com
Diabetic peripheral neuropathy (DPN) is the most common complication of both type 1 and 2
diabetes. As a result, neuropathic pain, diabetic foot ulcers and lower-limb amputations …

Diabetic neuropathy: A focus on small fibres

RA Malik - Diabetes/metabolism research and reviews, 2020 - Wiley Online Library
Diabetic peripheral neuropathy (DPN) is diagnosed too late, which contrasts with our
approach for diabetic retinopathy and nephropathy, where incipient disease is detected …

Diabetic peripheral neuropathy: diagnosis and treatment

J Røikjer, N Ejskjaer - Current Drug Safety, 2021 - ingentaconnect.com
Background: Diabetic peripheral neuropathy (DPN) is traditionally divided into large and
small fibre neuropathy (SFN). Damage to the large fibres can be detected using nerve …

Small nerve fiber quantification in the diagnosis of diabetic sensorimotor polyneuropathy: comparing corneal confocal microscopy with intraepidermal nerve fiber …

X Chen, J Graham, MA Dabbah, IN Petropoulos… - Diabetes …, 2015 - Am Diabetes Assoc
OBJECTIVE Quantitative assessment of small fiber damage is key to the early diagnosis and
assessment of progression or regression of diabetic sensorimotor polyneuropathy (DSPN) …

Diagnostic utility of corneal confocal microscopy and intra-epidermal nerve fibre density in diabetic neuropathy

U Alam, M Jeziorska, IN Petropoulos, O Asghar… - PloS one, 2017 - journals.plos.org
Objectives Corneal confocal microscopy (CCM) is a rapid, non-invasive, reproducible
technique that quantifies small nerve fibres. We have compared the diagnostic capability of …

[PDF][PDF] Diagnosing diabetic neuropathy: something old, something new

IN Petropoulos, G Ponirakis, A Khan… - Diabetes & …, 2018 - synapse.koreamed.org
There are potentially many ways of assessing diabetic peripheral neuropathy (DPN).
However, they do not fulfill US Food and Drug Administration (FDA) requirements in relation …

Gold standard for diagnosis of DPN

Y Yu - Frontiers in endocrinology, 2021 - frontiersin.org
Diabetic peripheral neuropathy (DPN) is a common complication of diabetes mellitus. It often
causes symmetrical paresthesia, loss of sensation, and hyperalgesia. Without early …

Corneal confocal microscopy to assess diabetic neuropathy: an eye on the foot

M Tavakoli, IN Petropoulos… - Journal of diabetes …, 2013 - journals.sagepub.com
Accurate detection and quantification of human diabetic peripheral neuropathy are important
to define at-risk patients, anticipate deterioration, and assess new therapies. Easily …

Small fibre neuropathy: role in the diagnosis of diabetic sensorimotor polyneuropathy

RA Malik, A Veves, S Tesfaye, G Smith… - Diabetes/metabolism …, 2011 - Wiley Online Library
Abstract Small fibres constitute 70–90% of peripheral nerve fibres and regulate several key
functions such as tissue blood flow, temperature and pain perception as well as sweating, all …

Corneal confocal microscopy compared with quantitative sensory testing and nerve conduction for diagnosing and stratifying the severity of diabetic peripheral …

M Ferdousi, A Kalteniece, S Azmi… - BMJ Open Diabetes …, 2020 - drc.bmj.com
Introduction Diabetic neuropathy can be diagnosed and assessed using a number of
techniques including corneal confocal microscopy (CCM). Research design and methods …